Abstract: Objective To explore the application value of massive open online courses(MOOC)teaching method combined with case-based learning(CBL)in the standardized residency training of medical imaging and the advanced training of radiologists.Methods From March 2016 to June 2020,65 students for standardized residency training and 73 radiologists for advanced training were enrolled in this study.They were divided into MOOC combined with CBL group, MOOC only and CBL only group.After 6 months training, theoretical assessment and practical ability(reading films)assessment were conducted to compare the learning results between different teaching groups of the students for standardized residency training and radiologists for advanced training.Results There were significant differences in theoretical assessment and practical ability between different groups of standardized training students(P<0.01); the MOOC combined with CBL group showed best theoretical assessment and practical ability, which were significantly better than MOOC only group(P<0.01)and CBL only group(P<0.01).There were significant differences in theoretical assessment and practical ability between different groups of advanced training radiologist(P<0.01); besides, the theoretical assessment scores showed no significant difference between MOOC combined CBL group and MOOC only group(P=0.21), and the practical ability showed no significant difference between MOOC combined CBL group and CBL only group(P=0.29).Conclusion The combination of MOOC and CBL teaching showed great advantage in standardized residency training and advanced training of radiologists.

Key words: imaging medicine, massive open online courses, case-based learning, education

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