Table of Content

25 June 2016, Volume 33 Issue 3

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Protection of Rosuvastatin combined with Diltiazem in patients with AMI undergoing percutaneous coronary intervention

ZHANG Lanfang,JIA Xinwei,WANG Zhanqi,XIE Junmin,HAN Kunpeng

2016, 33(3):  1-5.  DOI: 10.3969/j.issn.1674-490X.2016.03.001

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Objective To discuss the myocardial protection of Rosuvastatin combined with Diltiazem in patients undergoing percutaneous coronary intervention(PCI).Methods 150 patients with acute myocardial infarction(AMI)undergoing PCI were divided into group A(n=72)and group B(n=78).Both groups received high-dose rosuvastatin befor PCI and diltiazem by injecting intrainfarct-related artery,group A received diltiazem through continuous intravenous infusion additionally.The biochemical indexes,Thrombolysis In Myocardial Infarction(TIMI)and ST segment drop rate after 90 minutes were counted.Results Compared with the group B,the bochemical indexes decreased and rate of TIMI3,ST segment drop rate after 90 minutes increased obviously in group A.Conclusion High-dose rosuvastatin combined with diltiazem injection intrainfarct-related artery and intravenous infusion can protect myocardial.

Protection of Rosuvastatin combined with Diltiazem in patients with AMI undergoing percutaneous coronary intervention

ZHANG Lanfang,JIA Xinwei,WANG Zhanqi,XIE Junmin,HAN Kunpeng

2016, 33(3):  1-5.  DOI: 10.3969/j.issn.1674-490X.2016.03.001

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Objective To discuss the myocardial protection of Rosuvastatin combined with Diltiazem in patients undergoing percutaneous coronary intervention(PCI).Methods 150 patients with acute myocardial infarction(AMI)undergoing PCI were divided into group A(n=72)and group B(n=78).Both groups received high-dose rosuvastatin befor PCI and diltiazem by injecting intrainfarct-related artery,group A received diltiazem through continuous intravenous infusion additionally.The biochemical indexes,Thrombolysis In Myocardial Infarction(TIMI)and ST segment drop rate after 90 minutes were counted.Results Compared with the group B,the bochemical indexes decreased and rate of TIMI3,ST segment drop rate after 90 minutes increased obviously in group A.Conclusion High-dose rosuvastatin combined with diltiazem injection intrainfarct-related artery and intravenous infusion can protect myocardial.

Discussion on the diagnosis and treatment of Lisfranc injury combined with lateral malleolus fracture(Report of 8 cases)

FAN Hongqi,LIU Jianpeng,YAO Xuefeng,YANG Hongzhi,LI Xuefeng

2016, 33(3):  6-9.  DOI: 10.3969/j.issn.1674-490X.2016.03.002

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Objective To study the diagnosis and treating mechanism of Lisfranc injury associated with lateral malleolus fracture. Methods From December 2014 to January 2013 in two hospitals, the curative effects of reduction with internal fixation in all cases with Lisfranc injury associated with lateral malleolus fracture were analyzed retrospectively. The American Orthopaedic Foot and Ankle Society(AOFAS)scoring system was applied in the study. Results The results indicated that after follow-up study for 6 to 24 months(average, 15 months),the treating effects of fracture and dislocation healing were satisfactory in 8 case,with an average of 86 points in AOFAS score. Conclusion In the case of Lisfranc joint injury,the complete reduction and internal fixation of the fracture and dislocation can provide an excellent environment for the healing of the ligament and soft tissue injury. The lateral malleolus fracture associated with Lisfranc injuries is a low incidence of events,its injury mechanism could be caused by indirect force.

Application of general anesthesia combined with epidural anesthesia in elderly patients with surgery

SU Xiaohua, SU Hong, CAI Qiaoying, CHEN Jing

2016, 33(3):  10-15.  DOI: 10.3969/j.issn.1674-490X.2016.03.003

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Objective To investigate the effect of general anesthesia combined with epidural anesthesia in elderly patients with surgery. Methods 100 cases of elderly patients with surgery in our hospital from August to December 2015 were randomly divided into the observation group and the control group, the control group was given general anesthesia, the observation group was given epidural anesthesia, the hemodynamics and postoperative recovery time, recovery period, cognitive avoidance obstacle and security of two groups were compared. Results The results indicated that the blood pressure and heart rate at 3 min after intubation, surgical operation and extubation in the observation group were lower than that in the control group, wake up, extubation and response time were shorter than that in the control group, the difference was statistically significant(P<0.05). The rate of pain in observation group were lower than that in the control group, the MMSE score in 24 h and 12 h after operation were lower than that in control group, and the difference were statistically significant(P<0.05). The adverse reactions between the two groups were not statistically significant(χ²=0.796,P>0.05). Conclusion General anesthesia combined with epidural anesthesia can maintain the stability of vital signs, improve the awakening quality and reduce the incidence of postoperative cognitive impairment.

Traditional Chinese medicine’s medication rule of polycythemia vera and its translational medicine study

ZHANG Jianhong,LIU Panying,LI Yuan,ZHAO Tingting

2016, 33(3):  16-21.  DOI: 10.3969/j.issn.1674-490X.2016.03.004

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Objective To explore the Chinese medicine dialectical medication rule of polycythemia vera by applying translational medicine study to promote the process of new drug research and development.Methods The relevent medical case of TCM treatment of polycythemia vera disease were collected and analyzed by using Chinese medicine inheritance auxiliary system software data to explore polycythemia vera syndrome of TCM drug laws,and find new drug prescriptions.Results Based on 81 medical records,the appearance frequency of common syndromes,treatment,frequency of drug and the association rules between drugs were examined,32 core combinations and seven new prescriptions were also determined from the database.Conclusion Chinese medicines are commonly used in promoting blood circulation to remove blood stasis,clear heat and nourish Yin,clear heat and detoxicate,clear the liver and drain the fire efficacy to treat polycythemia vera disease.By using translational medicine conception to study this disease can apply its research achievements quickly to clinical practice.

Influence factors of SCL-90 factor of college journal editors

WANG Feiran,GAO Yanhua,LIU Guoyi,WANG Zheng

2016, 33(3):  22-28.  DOI: 10.3969/j.issn.1674-490X.2016.03.005

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Objective To explore the influence factors of SCL-90 factor of college journal editors.Methods SCL-90 score of 196 college journal editors was rated by using multivariate Logistic regression analysis on the influencing factors of each factors.Results Low professional titles and old working age were risk factors to somatization.Male,low education and having administrative positions were risk factors to compulsion.Male,low education,having administrative positions,old working age and engaged in other work were risk factors to interpersonal sensitivity.Low education,low professional titles,and old working age were risk factors to depression.Old working age was risk factor to anxiety.Male,low professional titles and old working age were risk factors to hostile.Low professional titles,having administrative positions,old working age and engaged in other work were risk factors to terror.Male,low professional titles,having administrative duties,old working age and engaged in other work were risk factors to bigotry.Male,low educational,low professional titles and old working age were risk factors to psychoticism.Old working age was risk factors to other factors(especially the situation of sleeping and eating).Conclusion Although the influencing factors of different SCL-90 factors of college journal editors vary,but the main parts are working age,gender and the professional title.Male college journal editors with low professional title should be paied more attention.

The effects of telephone follow-up continuity of care on non-medicine measure of secondary prevention of patients with coronary heart disease

YANG Hui,WU Di

2016, 33(3):  29-33.  DOI: 10.3969/j.issn.1674-490X.2016.03.006

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Objective To probe into influence of telephone follow-up continuity of care on non-medicine measure of secondary prevention of patients with coronary heart disease.Methods 68 patients with coronary heart disease after discharge were regular followed up and carried out health education intervention.Life style score was investigated before and after intervention,including diet,no smoking,physical exercise and emotional control.Results Life style score was changed significantly except emotional control.Conclusion Telephone follow-up continuity of care on non-medicine measure of secondary prevention can improve life style.The intervention of emotional control should be strengthened.

Discussion on postoperative nursing care in patients with thyroid nodules(Report of 536 cases)

GONG Jianping,LI Yunyao,WENG Peishan,ZHANG Caifen,YANG Jiuyi

2016, 33(3):  34-37.  DOI: 10.3969/j.issn.1674-490X.2016.03.007

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Objective To investigate the clinical nursing effect of thyroid nodules after operation. Methods Retrospective analysis of clinical nursing data in 536 patients with thyroid nodules from Affiliated Hospital of Hebei University from June 2010 to June 2015 were carried out.Results Among 536 cases,34 cases showed postoperative hypocalcemia convulsions,two cases occurred nausea and vomiting,after appropriate treatments they were restored to normal.The average postoperative hospitalization time was(8.1±2.8)d,all were discharged from the hospital. After conducting follow up-study for 3 to 6 months,there was no recurrence in the patients.Conclusion Paying close observation after operation,conducting basic nursing,giving life guidance,psychological care,timely treatment of complications are key measures to the rehabilitation of the patients,which are worthy of widely application in clinical practices.

Study on application of clinical nursing path form to prevent and treat postpartum hemorrhage in puerperal women

WANG Hongyan,ZHANG Ruihong,ZHU Minjing

2016, 33(3):  38-41.  DOI: 10.3969/j.issn.1674-490X.2016.03.008

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Objective To detect the abnormal symptoms early and prevent severe complications in the puerpral women. Methods Nurses observed the puerpral women and recorded the abnormal symptoms following the postpartum nursing clinical path forms which was developed according to the reference books and clinical data,collected and analysed the related data of six months from January to July in 2015 and 2014.Results Tha cases of postpartum hemorrage in 2015 were compared with that of 2014,there were no significant differences.Compared the data of 2014,the cases of blood transfusion resulted from severe postpartum hemorrhage in 2015 were less than that of 2014,the rates of abnormal symptoms detected by nurses in 2015 were more than that of 2014,there were signi ficant differences.Conclusion Nurses behavior can be regulated,especially the new hirely nurses. The abnormal symptoms can be detected early in puerpera with employing the clinical nursing path form which was scientific, practical and simple. Postpartum hemorrhage and other’s complications can be prevented and treated in the early stage with the use of the form.

Advances on research of metabolomics in malignant cancer diagnosis

LI Yumeng,CHEN Ying

2016, 33(3):  42-46.  DOI: 10.3969/j.issn.1674-490X.2016.03.009

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Metabolomics for biological metabolite changes was widely accepted,the study of metabolomics is becoming a powerful tool for disease diagnosis and disease mechanism in recent years.In this paper,we review the recent applications of metabonomics study in the diagnosis of malignant tumor.Literatures about the study of metabonomics in the diagnosis of malignant tumor were summarized according to the classification of tumors.In recent years,metabolomics is widely used in cancer diagnosis,mainly in gastric cancer,liver cancer,lung cancer,esophageal cancer,breast cancer,ovarian cancer,prostate cancer,et al.Metabolomics play important role in the aspects of cancer pathogenesis,early diagnosis,differential diagnosis,staging and prognosis.With the development of analysis techniques,metabolomics will become an important method in the research of malignant tumor.

Developments on surgical treatment of femoral shaft fracture

LI Yawei,TIAN Yue

2016, 33(3):  47-51.  DOI: 10.3969/j.issn.1674-490X.2016.03.010

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Femoral shaft fracture occurred in the adult population associated with high energy injury,special and thigh anatomy,the majority of patients with fracture displacement often need surgical treatment.Nearly half a century,with the improvement and innovation of fixed equipment,the operative treatment ways of femoral shaft fracture are gradually increasing.Surgical treatment progress are summarized as follows, which may provide certain references for follow-up treatment program of femoral shaft fracture.

Advances on the treatment of angina pectoris symptoms of coronary heart disease with Tongxinluo capsule

HUANG Yaqin,XIA Yueping,NUI Pei

2016, 33(3):  52-56.  DOI: 10.3969/j.issn.1674-490X.2016.03.011

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With the development of China's population aging,the incidence rate of coronary heart disease is gradually increasing.Angina pectoris is an important symptom of coronary heart disease.In China,it is commonly used in the control of angina pectoris with beta blockers,calcium channel blockers and nitrates.Besides,it also has the traditional Chinese medicine Tongxinluo capsule.At present,through a series of clinical trials and research findings indicated that it has a certain efficacy and safety,which can effectively improve and ease coronary heart disease patients with angina pectoris,reduce the side effect caused by large doses of medicine,it is worth promoting in clinical use.

Problems and countermeasures of classroom teaching for pathology in university

JI Hairu,KONG Lingwei,CHENG Yu,ZHENG Jining,ZHAO Shumin

2016, 33(3):  57-59.  DOI: 10.3969/j.issn.1674-490X.2016.03.012

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Pathology is the bridge between basic theoretical coures and clinical practice lessons,to learn pathology well is the benefit for students transiting from the theoretical foundation to the clinical practice.With the rapid development of information technology and popularization of network technology, there are many new problems and stituations in teaching pathology. This article provides a new train of thought for pathology teaching through exploring pathology network study, theoretical study and learning methods.

Investigation on needs analysis of medical English teaching in medical workers

TANG Chongwen,WANG Qi,WU Yina,SUN Xuemei,CHI Honghua

2016, 33(3):  60-62.  DOI: 10.3969/j.issn.1674-490X.2016.03.013

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The needs for medical English among 186 medical workers from 5 medical departments were investigated via questionnaires and interviews,based on a detailed analysis of the results,several suggestions were put forward to address the issues in medical English teaching.

Analysis on the feasibility of tutorial system on scientific research for medical undergraduates——Hebei University as an example

QI Chang,JIA Sinong,LI Lin,LIU Suping,ZHANG Hongjie

2016, 33(3):  63-68.  DOI: 10.3969/j.issn.1674-490X.2016.03.014

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Objective To explore the feasibility of on scientific research for medical undergraduates.Methods Questionnaire survey was conducted with stratified cluster sampling method,and the situation,the participation of tutorial system and its influencing factors among medical undergraduates were analyzed.Results The medical undergraduates involved in scientific research accounted for 16.98%,and those who were willing to take the initiative to participate in the tutorial system students accounted for 84.59%.For participation intention to the tutorial system,females were stronger than that of the males ［OR=2.179,95% CI(1.375-3.454)］. The higher the grade,the lower the active participation ［OR=0.786,95% CI(0.632-0.978)］,students who plan to continue with postgraduate education or join in a push avoid unripe had a lower participation rate than the others ［OR=0.337,95% CI(0.204-0.558)］.Conclusion The participation intention of early scientific research in medical undergraduates is strongly,and gender,grade and whether to continue with postgraduate education are independent influencing factors.The implementation of research tutorial system in medical undergraduate is feasible.

The comparison between CBL, PBL methods and traditional methods in teaching of clinical genetics

YUAN Jihang, WANG Fang, SUN Shuhan

2016, 33(3):  69-72.  DOI: 10.3969/j.issn.1674-490X.2016.03.015

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Objective To investigate the effects of CBL, PBL methods in teaching clinical genetics. Methods 60 students majored in clinical medicine of 2013 grade, Second Military Medical University were divided into two groups with 30 students in each group. The students in experimental group were taught with CBL, PBL methods. The students in control group were taught with traditional methods. The teaching effects were evaluated by satisfaction questionnaires and quiz scores. Results The quiz scores of experimental group were better than that of control group. The satisfaction rate to CBL, PBL methods was above 80%. Conclusion Applying CBL, PBL methods in teaching clinical genetics can improve teaching effects significantly, and can better motivate activeness of students’ autonomic learning and promote the binding of theory to practice skills.