核磁负担评分与轻型脑卒中早期神经功能恶化的相关性

doi:10.3969/j.issn.1674-490X.2023.04.003

医学研究与教育 ›› 2023, Vol. 40 ›› Issue (4): 19-24.DOI: 10.3969/j.issn.1674-490X.2023.04.003

核磁负担评分与轻型脑卒中早期神经功能恶化的相关性

卢丹丹,王佩,李蒙蒙,万莉,李轩,赵婧

1.保定市第一中心医院神经内三科, 河北保定 071000;
2.保定市神经系统疾病研究重点实验室, 河北保定 071000

收稿日期:2023-02-22 出版日期:2023-08-25 发布日期:2023-08-25
通讯作者: 王佩(1971—),女,河北辛集人,教授,主任医师,博士,硕士生导师,主要从事脑血管病的研究。E-mail: w_z_h_01@163.com
作者简介:卢丹丹(1990—),女,河北定州人,主治医师,硕士,主要从事脑血管病研究。 E-mail: ludandan22@sina.com
基金资助:
河北省医学研究重点课题计划项目(20181487);保定市科学技术研究与发展计划项目(2041ZF246)

Received:2023-02-22 Online:2023-08-25 Published:2023-08-25

摘要/Abstract

摘要： 目的探讨核磁负担评分与轻型脑卒中早期神经功能恶化的相关性。方法回顾性分析2018年6月至2020年12月住院的缺血性轻型脑卒中患者395例,根据早期神经功能恶化情况分为恶化组(n=36)及常规组(n=359),分析性别、年龄、既往病史(高血压、糖尿病等)、核磁负担评分、基线收缩压、血脂、同型半胱氨酸等与早期神经功能恶化的关系。结果早期神经功能恶化组核磁负担评分高于常规组(P<0.05),Logistic回归分析发现,核磁负担评分为轻型脑卒中患者早期神经功能恶化的独立危险因素(P<0.05)。结论轻型脑卒中患者核磁负担评分越高,早期神经功能恶化的风险越高。

关键词: 核磁负担评分, 早期神经功能恶化, 轻型脑卒中, 脑白质疏松, 腔隙性脑梗死, 脑微出血, 血管周围间隙

Abstract: Objective To investigate the correlation between MRI burden score and early deterioration of neurological function in patients with mild stroke. Methods Retrospective analysis of 395 inpatients with ischemic stroke in June, 2018 to December, 2020 were conducted. According to the early neurological deterioration, the patients were divided into the worsening group(n=36)and the conventional group(n=359). The relationship between gender, age, past history(hypertension, diabetes,et al), nuclear magnetic resonance score, baseline systolic blood pressure,blood lipids, homocysteine and other neurological deterioration were analyzed. Results The MRI burden score in the early neurological deterioration group was higher than that in the routine group(P<0.05). Logistic regression analysis found that MRI burden score were independent risk factors for early neurological deterioration in patients with mild stroke(P<0.05). Conclusion The higher the MRI burden score, the higher risk of early neurological deterioration in patients with mild stroke.

Key words: MRI burden score, early neurological deterioration, minor stroke, cerebral leukosoporosis, lacunar cerebral infarction, microhemorrhage in the brain, perivascular space

中图分类号:

卢丹丹,王佩,李蒙蒙,万莉,李轩,赵婧. 核磁负担评分与轻型脑卒中早期神经功能恶化的相关性[J]. 医学研究与教育, 2023, 40(4): 19-24.

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核磁负担评分与轻型脑卒中早期神经功能恶化的相关性

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