医学研究与教育 ›› 2019, Vol. 36 ›› Issue (5): 19-23.DOI: 10.3969/j.issn.1674-490X.2019.05.004

• 临床医学 • 上一篇    下一篇

定量磁敏感图对脑微出血的诊断价值

苏辰1,王淑梅2,郝永2,刘冲2,张建军2   

  1. 1.承德医学院研究生学院, 河北 承德 067000;
    2.保定市第一中心医院医学影像科, 河北 保定 071000
  • 收稿日期:2019-08-17 出版日期:2019-10-25 发布日期:2019-10-25
  • 通讯作者: 王淑梅(1963—),女,黑龙江哈尔滨人,主任医师,教授,硕士生导师, 主要从事CT及MRI诊断。E-mail: Wangshum588@sohu.com
  • 作者简介:苏辰(1994—),男,河北保定人,在读硕士,主要从事影像医学与核医学研究。

  • Received:2019-08-17 Online:2019-10-25 Published:2019-10-25

摘要: 目的 探讨定量磁敏感图(quantitative susceptibility mapping,QSM)在脑微出血(cerebral microbleeds,CMBs)中的临床应用价值。方法 对122例拟诊脑血管病患者进行头颅MRI常规序列扫描(包括T1、T2、T2FLAIR序列)并做SWI及QSM序列成像检查,这些患者全部在1周内做了头颅CT平扫,全部患者检查成功,分别获得基底节区及基底节区以外区域的CMBs个数,并做相应统计学分析。结果 122例拟诊脑血管病患者中,80例有CMBs,42例未检出,二者共检出CMBs 481个,其中QSM序列共检出CMBs 481个,SWI序列共检出CMBs 447个,比较2种序列对CMBs总的检出率,差异有统计学意义(P<0.05),2种序列对基底节及基底节外区CMBs检出率,差异具有统计学意义(P<0.05)。结论 QSM序列对CMBs检出率优于SWI序列,是一种准确可靠的诊断CMBs的影像学方法。

关键词: 磁共振成像, 定量磁敏感图, 磁敏感加权成像, 脑微出血

Abstract: Objective To investigate the clinical value of quantitative susceptibility mapping(QSM)in cerebral microbleeds(CMBs). Methods 122 patients with cerebrovascular disease were enrolled in the routine MRI sequence including T1,T2,T2FLAIR sequences and SWI and QSM sequence imaging. All patients underwent a CT scan of the head within one week. The patients were examined,successfully,the number of microbleeds in the basal ganglia and the area outside the basal ganglia were obtained,and the corresponding statistical analysis was performed. Results Of the 122 patients with cerebrovascular disease,80 had cerebral microbleeds and 42 were not detected. A total of 481 microbleeds were detected. Among them,481 cerebral microbleeds were detected in the QSM sequence. 447 cerebral microbleeds were detected,and the total detection rate of CMBs was statistically significant(P<0.05). The difference between the two groups in the detection of CMBs in each region was statistically significant(P<0.05). Conclusion The detection rate of CMBs in QSM sequences is better than that in SWI sequences,which is an accurate and reliable imaging method for diagnosing CMBs.

Key words: magnetic resonance imaging, quantitative susceptibility mapping, susceptibility weighted imaging, cerebral microbleeds

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