甲状腺功能亢进与动脉粥样硬化的相关性研究

医学研究与教育 ›› 2014, Vol. 31 ›› Issue (6): 24-27.

甲状腺功能亢进与动脉粥样硬化的相关性研究

巩建萍，郭雅卿，尹娟，张海容，连雪，谢瑾，杨久宜

河北大学附属医院，河北保定 071000

出版日期:2014-12-25 发布日期:2014-12-25
通讯作者: 郭雅卿（1973—），女，河北保定市，硕士，副主任医师，主要从事内分泌疾病研究。E-mail: yaqing_guo2010@163.com
作者简介:巩建萍（1971—），女，河北保定人，副主任检验师，主要从事临床检验及健康管理研究。

Study on atherosclerosis in the patients with hyperthyroidism

GONG Jianping, GUO Yaqing, YIN Juan,ZHANG Hairong, LIAN Xue, XIE Jin, YANG Jiuyi

Affiliated Hospital of Hebei University,Baoding 071000,China

Online:2014-12-25 Published:2014-12-25

摘要/Abstract

摘要： 目的探讨甲状腺功能亢进患者动脉粥样硬化情况，以了解甲状腺功能亢进与动脉粥样硬化关系。方法选择甲亢患者 72 例与对照组 63 例进行颈动脉超声及血液生化检查，观察 2 组的 CIMT、ET、NO 及 CRP情况。结果 CIMT 在 45 岁以上甲亢组明显高于 45 岁以下甲亢组与对照组，差异具有统计学意义（P<0.05）；CIMT 在 45 岁以上甲亢组及对照组中差异无统计学意义（P>0．05）。ET、NO 及 CRP 水平在甲亢组中高于正常组，差异具有统计学意义（P<0.05）。结论甲亢可引起血管内皮损害，发生动脉粥样硬化的风险增高。

关键词: 甲状腺功能亢进, 动脉粥样硬化, CIMT

Abstract: Objective To investigate the characteristics of carotid atherosclerotic lesions in patients with hyperthyroidism. Methods 72 patients with hyperthyroidism ( hyperthyroidism group) and 63 cases of healthy volunteers ( control group) were investigated, the changes of CIMT, ET, NO, CRP were observed. Results CIMT in hyperthyroidism group with above 45 years old was higher than those of the hyperthyroidism group and control group with Less than 45 years old. The levels of ET, NO, CRP in hyperthyroidism group were higher than those of the control group. Conclusion Hyperthyroidism is associated with endothelial damage and increase the risk of atherosclerosis

Key words: hyperthyroidism, atherosclerosis, CIMT

中图分类号:

R563

巩建萍，郭雅卿，尹娟，张海容，连雪，谢瑾，杨久宜. 甲状腺功能亢进与动脉粥样硬化的相关性研究[J]. 医学研究与教育, 2014, 31(6): 24-27.

GONG Jianping, GUO Yaqing, YIN Juan,ZHANG Hairong, LIAN Xue, XIE Jin, YANG Jiuyi. Study on atherosclerosis in the patients with hyperthyroidism[J]. Medical Reserch and Education, 2014, 31(6): 24-27.

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