合并睡眠呼吸暂停的中青年脑梗死患者颈动脉粥样硬化的研究

doi:10.3969/j.issn.1674-490X.2015.06.006

医学研究与教育 ›› 2015, Vol. 32 ›› Issue (6): 30-33.DOI: 10.3969/j.issn.1674-490X.2015.06.006

合并睡眠呼吸暂停的中青年脑梗死患者颈动脉粥样硬化的研究

赵慧新，孟亚楠，张杏红，苏立凯，甄景，王杏微，史福平

河北大学附属医院神经内科，河北保定 071000

出版日期:2015-12-25 发布日期:2015-12-25
通讯作者: 史福平（1973-），女，河北保定人，硕士，副主任医师，主要从事脑血管病研究。 E-mail： huandeng2003@163.com
作者简介:赵慧新（1978-），女，河北唐山人，硕士，主治医师，主要从事脑血管病研究。
基金资助:
河北省科学技术研究与发展计划项目（12276104D-81）

Study of carotid atherosclerosis in middle-aged and young patients of cerebral infarction with sleep apnea-hypopnea

ZHAO Huixin, MENG Yanan, ZHANG Xinghong, SU Likai, ZHEN Jing, WANG Xingwei, SHI Fuping

Affiliated Hospital of Hebei University, Baoding 071000, China

Online:2015-12-25 Published:2015-12-25

摘要/Abstract

摘要： 目的探讨合并睡眠呼吸暂停（sleep apnea-hypopnea，SA）的中青年脑梗死（cerebral infarction，CI）患者颈动脉粥样硬化（carotid atherosclerosis，CAS）情况。方法 80 例中青年脑梗死患者分为单纯 CI 组（40 例）、CI 合并 SA 组（40 例），两组患者均行颈动脉彩色多普勒超声检查，记录颈动脉内中膜厚度（intima-media thickness，IMT）及斑块情况。结果中青年 CI 合并 SA 组及单纯 CI 组患者颈动脉 IMT 分别为 (1.335±0.219)mm、(1.088±0.202)mm，CI 合并 SA 组高于单纯 CI 组（P<0.01）,CI 合并 SA 组及单纯 CI 组患者斑块发生率分别为 75%、25%，CI 合并 SA 组高于单纯 CI 组（P<0.01），CI 合并 SA 组及单纯 CI 组患者不稳定斑块发生率分别为 71%、30%，CI 合并 SA 组高于单纯 CI 组（P<0.05）。结论中青年 CI 合并 SA 患者颈动脉粥样硬化程度更重。

关键词: 脑梗死, 睡眠呼吸暂停, 颈动脉粥样硬化, 中青年

Abstract: Objective To investigate the carotid atherosclerosis(CAS)in middle-aged and young patients of cerebral infarction (CI) with sleep apnea-hypopnea (SA). Methods 80 middle-aged and young patients of CI were divided into two groups, only CI group (40 cases)) and CI combined with SA group (cases 40).All patients were checked carotid artery through color doppler ultrasound and record intima-media thickness(IMT) and the state of plaques. Results The IMT of middle-aged and young patients in CI combined with SA group and in only CI group were (1.335±0.219)mm,(1.088±0.202)mm respectively, the degree of IMT in CI combined with SA group was significantly higher than that in only CI group (P<0.01).The rate of plaque occurrence in CI combined with SA group and in only CI group were 75%,25% respectively, the rate of plaque occurrence in CI combined with SA group was significantly higher than that in only CI group (P<0.01).The rate of unstable plaque occurrence in CI combined with SA group and in only CI group were 71%,30% respectively, the rate of unstable plaque occurrence in CI with SA group was significantly higher than that in only CI group (P<0.05). Conclusion There is higher degree of carotid artery atherosclerosis in the middle-aged and young patients of CI combined with SA group than that of only CI group.

Key words: cerebral infarction, sleep apnea-hypopnea, carotid atherosclerosis, middle-aged and young patients

中图分类号:

赵慧新，孟亚楠，张杏红，苏立凯，甄景，王杏微，史福平. 合并睡眠呼吸暂停的中青年脑梗死患者颈动脉粥样硬化的研究[J]. 医学研究与教育, 2015, 32(6): 30-33.

ZHAO Huixin, MENG Yanan, ZHANG Xinghong, SU Likai, ZHEN Jing, WANG Xingwei, SHI Fuping. Study of carotid atherosclerosis in middle-aged and young patients of cerebral infarction with sleep apnea-hypopnea[J]. Medical Reserch and Education, 2015, 32(6): 30-33.

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合并睡眠呼吸暂停的中青年脑梗死患者颈动脉粥样硬化的研究

Study of carotid atherosclerosis in middle-aged and young patients of cerebral infarction with sleep apnea-hypopnea

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