Abstract: Objective To study the application of PBL in experimental teaching of epidemiology in the student of clinical medicine. Methods 152 students were selected. They were divided into the PBL group and traditional method group at random. The teaching effects of two groups were compared. Results The excellent rates of PBL group was higher than that of the traditional method group. conclusion PBL can effectively increase the teaching quality of epidemiology.

Key words: problem-based learning, clinical medicine, epidemiology