Effects of different iIntensity of magnetic field on peripheral nerve scar formation in rats

Medical Reserch and Education ›› 2014, Vol. 31 ›› Issue (6): 5-9.

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Effects of different iIntensity of magnetic field on peripheral nerve scar formation in rats

ZHOU Cheng¹, JIANG Yuantao², XUE Jinwei², ZHANG Ke², ZHANG Zhijun³, CHEN Honggang⁴, DU Linzhe⁵, LIU Shuangli⁶

1. Hebei University, Baoding 071000, China; 2. Affiliated Hospital of Hebei University, Baoding 071000, China; 3. Dingxing County Hospital, Dingxing 072650, China; 4. Wangdu County Hospital, Wangdu 072450, China; 5. Laiyuan County Hospital, Laiyuan 074100, China; 6. The 252 Hospital of PLA, Baoding 071000, China

Online:2014-12-25 Published:2014-12-25

Abstract

Abstract: Objective To observe how magnetic field interference effect on nerve scar formation after nerve injury in rats. Methods 80 SD rats were implemented left sciatic nerve entrapment surgery, with nerve damaged. After surgery, the rats were randomly divided into four groups: 1 control group and 3 experimental groups. Experimental groups were respectively given 0.2 mT’s, 0.6 mT’s, and 1.5 mT’s intensity magnetic therapy, 60 min/d. Sciatic nerve function index measurement (SFI) was tested in 21 days. After drawn, the samples were applied, type collagen fibers immunohistochemical staining, transmission electron microscope and experimental data statistics processing were performed. Results Compared with the control group, the experimental group was closer to normal in nerve function index, with less, type collagen fibers hyperplasia in Nerve lesions, thicker myelin sheath and line rules walking.Conclusion Magnetic field interference can significantly inhibit scar formation, promote nerve regeneration and functional recovery.

Key words: magnetic field, nerve injury, nerve scar, collagen fiber

CLC Number:

ZHOU Cheng, JIANG Yuantao, XUE Jinwei, ZHANG Ke, ZHANG Zhijun, CHEN Honggang, DU Linzhe, LIU Shuangli. Effects of different iIntensity of magnetic field on peripheral nerve scar formation in rats[J]. Medical Reserch and Education, 2014, 31(6): 5-9.

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Effects of different iIntensity of magnetic field on peripheral nerve scar formation in rats

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