Abstract: Objective To observe the safety of gastroscope examination with Remifentanil and nursing approaches in old patients. Methods 100 patients were assigned randomly into two groups. 50 patients in group Propofol were treated with Propofol 1-1.5 mg/kg, and 20-50 mg was added if necessary. Group Remifentanil was intravenously injected with Remifentanil 1 μg/kg before examination, and the medicine was continued injected with the speed of 0.1 μg/(kg·min). In the stage of examination, blood pressure, pulse and blood oxygen were recorded. Results The patients of group Propofol showed a slight inhibition of circulation and respiration, and the numerical values of blood pressure, pulse and blood oxygen were significantly changed in the stage of examination. The patients in group Remifentanil showed no difference. Conclusion The low dosage of Remifentanil can be used safely in gastroscope examination.

Key words: Remifentanil, awak-sedation gastroscope, nursing