Association of neutrophil-lymphocyte ratio with left atrial thrombus in patients with nonvalvular atrial ifbrillation

doi:10.3969/j.issn.1674-490X.2014.04.009

Abstract

Abstract: Objective To compare NLR among patients with nonvalvular atrial ifbrillation (AF) with or without left atrial (la) thrombus. Methods 155 patients with nonvalvular AF undergone transthoracic echocardiography (TTE) were selected to assess the presence of la thrombus. Baseline NLR was measured by dividing neutrophil count to lymphocyte count. Results Left atrial thrombus was detected in 16(10.3%) of 155 patients. Mean NLR (2.8 ± 1.2, 2.0 ± 1.1, P=0.023) was significantly higher among patients with la thrombus compared to patients without la thrombus. On multivariate analysis, NLR (odds ratio 1.78, 95%conifdence interval 1.93-4.24, P<0.001) was an independent risk factor for the presence of la thrombus in patients with nonvalvular AF. Conclusion Neutrophil-lymphocyte ratio, an emerging marker of inlfammation, is independently associated with the presence of la thrombus in patients with nonvalvular AF.

Key words: atrial ifbrillation, left atrial thrombus, inlfammation, neutrophil-lymphocyte ratio

CLC Number:

AN Yanxiao,LIU Keye,WANG Yang,LUO Zhiqiang,HAN Zhe,LIU Fulin. Association of neutrophil-lymphocyte ratio with left atrial thrombus in patients with nonvalvular atrial ifbrillation[J]. Medical Reserch and Education, 2014, 31(4): 34-37.

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