Journal of Hebei Medical College for Continuing Education

Effects of perna viridis polysaccharides on apoptosis of cervical cancer cell and expression of miRNA-34a

LAI Yinxuan,HE Dongmei,YANG Limei,LIU Xinguang,LI Jiangbin

2014, 31(2): 1-3. DOI: 10.3969/j.issn.1674-490X.2014.02.001

Asbtract ( 246 )

PDF (1240KB) ( 328 )

References | Related Articles | Metrics

Objective To investigate the effects of perna viridis polysaccharides (PVPS) on apoptosis of cervical cancer cell and expression of miRNA-34a. Methods Cervical cancer cells were treated with PVPS (100 mg/L) for 48 hours, then flow cytometry was used to analyse apoptosis and real-time quantitative PCR to detect expression of miRNA-34a. Results Compared with control group, PVPS can significantly rise the apoptosis rate (P<0.001) and expression of miRNA-34a (P<0.01) in cervical cancer cell. Conclusion PVPS can induce apoptosis of cervical cancer cell by elevate expression of miRNA-34a.

Research of relationship between matrix metalloproteinase-9 and carotid atherosclerosis plaque’s stability

SONG Yueping,SUN Juping,ZHOU Jinying,DI Weiying,LIU Dan,GAO Juan

2014, 31(2): 4-6. DOI: 10.3969/j.issn.1674-490X.2014.02.002

Asbtract ( 257 )

PDF (1293KB) ( 367 )

References | Related Articles | Metrics

Objective To study the relationship between matrix metalloproteinase-9 and carotid atherosclerosis plaque’s stability. Methods The bilateral carotid atherosclerosis of 48 asymptomatic carotid atherosclerosis patients(ACA group) and 20 normal controls(NC group) were examined with color Doppler. The serum levels of MMP-9 in all the groups were measured by enzyme linked immunosorbent assay. Results Carotid atherosclerosis plaque was not found in NC group. The serum levels of MMP-9 in ACA group were significantly higher than that in NC group(all P<0.05). In ACA group, the serum levels of MMP-9 in vulnerable plaque subgroup were significantly higher than that in stabled plaque subgroup(all P<0.05) and the serum levels of MMP-9 in stable plaque subgroup were signiifcantly higher than that in no plaque subgroup(all P<0.05). Conclusion The serum levels of MMP-9 can be serum markers of carotid atherosclerosis plaque and its stability index.

The impact of Iodixanol against kidney injury molecule-1 and the renal tubular cell apoptosis in rats with renal insufifciency

WANG Xianjun,WU Shangqin,YAO Qinghai,DONG Guofeng

2014, 31(2): 7-11. DOI: 10.3969/j.issn.1674-490X.2014.02.003

Asbtract ( 320 )

PDF (1384KB) ( 356 )

References | Related Articles | Metrics

Objective To observe the impact of Iodixanol against kidney injury molecule-1 and the renal tubular cell apoptosis in rats with renal insufifciency. Methods 48 male wistar rats were randomly divided into four groups:normal control group, model group, Iodixanol group1, Iodixanol group2 (n=12). Iodixanol groups and model group were applied the methods of left renal artery narrowing (30%), right nephrectomy to produce renal insufifciency model in rats respectively, in the preoperative and postoperative 2 weeks every other day by measuring the angular vein blood BUN, SCr and taking urine test of urinary kidney injury molecule-1 (KIM-1) values. After the ifrst three weeks of intravenous saline model group, iodixanol (5 mL/kg)injection of iodixanol group 1, iodixanol (10 mL/kg)injection of iodixanol group 2, the changes of blood urea nitrogen, creatinine and urinary KIM-1 of the two iodixanol groups before applying the contrast agent, after 3 h, 24 h, 48 h, 72 h and 7 d were observed. Three rats of each group were sacriifed in 24 h, 72 h and 7th day after injection of contrast agent. The renal tubular cell apoptosis rates were measured by TUNEL and the differences of each group were compared. Results After in the ifrst two days of surgery, serum BUN, SCr levels in model group were signiifcantly higher than that of the normal group (P<0. 0 1 ) and rised sharply up to about 2 times before surgery, Then gradually decreased after surgery stable at 1.5-2.0 times the preoperative levels two weeks. But the values of KIM-1 were no signiifcant difference (P>0.05). Compared with the model group, in 24 h, 72 h and 7th day after the injection of contrast agents, the values of BUN and SCr, the value of KIM-1 in urine and the rates of apoptosis of renal tubular cells in iodixanol group 2 were signiifcantly increased higher than that of the model group (P<0.01). After three hours iodixanol injection of iodixanol group 2, urinary KIM-1 levels that increased signiifcantly earlier than the rise in the iodixanol group1, the difference was signiifcant (P<0.01). Conclusion By using the left renal artery narrowing and right nephrectomy method can be prepared with mild to moderate chronic renal failure in animal models;iodixanol can cause acute kidney injury of chronic renal failure animals and the speciifc mechanisms may induce renal contrast agent tubule epithelial cell apoptosis. KIM-1 can be used as a contrast agent nephropathy early predictors. Different concentrations of contrast agents for renal tubular injury are different.

Effects of red LED lights on the regeneration of liver injury in rats

SUN Jiangang,LIU Shihao,DONG Hongwei,HOU Chenning,XIE Yinghui,LIU Zihao,WANG Xinyue,JI Kan,CUI Yan,LI Li

2014, 31(2): 12-16. DOI: 10.3969/j.issn.1674-490X.2014.02.004

Asbtract ( 292 )

PDF (1340KB) ( 399 )

References | Related Articles | Metrics

Objective To observe the effects of red light source on the liver regeneration of liver injury in rats. Methods Fifty experimental SD rats were randomly divided into five groups, normal control group, model group, 10 min irradiation group, 20 min irradiation group, and 30 min irradiation group, with 10 rats in each group. The blood sampling was undergone to test alanine aminotransferase and aspartate aminotransferase of all groups after 4 weeks. The livers were taken out and weighed to calculate the proportion of regeneration liver lobes weight. The liver tissues were taken to observe the regenerated liver cells of regeneration leaves with microscope. Results The alanine aminotransferase level of each treatment group was lower than that of model group (P<0.05). The aspartate aminotransferase level of the rats in 30 min irradiation group was decreased than those of model group (P<0.05). The results of pathology showed the liver cell regeneration of the treatment group was signiifcantly better than the model group (P<0.05). Compared with the model group, the proportion of the regeneration liver lobe in each treatment group was signiifcantly increased (P<0.05). Conclusion Red light could promote the regeneration capacity of the damaged liver, and help liver function recover of rats with liver injury.

Logistic regression analysis on inlfuencing factors of medical abortion outcome

LIU Meiyun,ZHANG Hongjie,ZHU Jihong,GAO Jing

2014, 31(2): 17-20. DOI: 10.3969/j.issn.1674-490X.2014.02.005

Asbtract ( 257 )

PDF (1328KB) ( 304 )

References | Related Articles | Metrics

Objective To explore the influencing factors of medical abortion outcome, and provide evidences for making intervention measures. Methods A case-control study was adopted with cases who had incomplete or failure abortion after medical abortion, and the controls were those who had complete abortion. The data was analyzed by SPSS16.0. Results The univariate analysis showed that factors such as the surgical abortion history (χ2=4.691, P=0.030), the site of the medical abortion (χ2=13.487, P=0.000), pregnant weeks (χ2=6.747, P=0.009), whether vaginitis before medical abortion (χ2=22.153, P=0.000) were influencing the medical abortion outcome. The multivariate analysis showed that risk factors were the site of the medical abortion (OR=3.693, P=0.009)and whether vaginitis before medical abortion (OR=4.520, P=0.000). Conclusion In private clinics, the ratio of incomplete abortion or failure of medical abortion was more than that in public hospital or family planning clinics. For the women with vaginitis, the possibility of incomplete abortion or failure was greater.

Sensitivity analysis on commonly used chemotherapy drugs in treating breast cancer cells

ZHOU Bin,Li Yuanyuan

2014, 31(2): 21-24. DOI: 10.3969/j.issn.1674-490X.2014.02.006

Asbtract ( 366 )

PDF (1305KB) ( 296 )

References | Related Articles | Metrics

Objective Through culturing breast cancer cells in vitro, and applying common chemotherapy drug sensitivity testing to provide clinical reference and choice of chemotherapy drugsto reduce the clinical chemotherapy choice blindness and get better implementation of individual treatment. Methods MTT method was applied in testing susceptibility of the tumor cells and tumor cells cultured in vitro in surgical resection of lung cancer (13 cases), esophageal cancer (4 cases). Results 16 kinds of chemotherapeutic drugs with high sensitivity to lung squamous cell carcinoma were the following:oxaliplatin (60%), cisplatin, cyclophosphamide, paclitaxel (40%). 16 kinds of chemotherapeutic drugs with high sensitivity to lung cancer were the followings:vinorelbine, paclitaxel, fluorouracil (63%). 16 kinds of chemotherapeutic drugs with high sensitivity to esophageal squamous cell carcinoma were the followings:Navelbine, vincristine, topotecan (75%). Conclusion Susceptibility testing of tumor cells in vitro has guiding significance for reasonable choice of breast cancer chemotherapy.

Analysis of the death causes of patients with hypertensive intracerebral hemorrhage after operation

SONG Chaoyan,XIE Dong,DONG Xiaohui,WANG Chunsheng

2014, 31(2): 25-29. DOI: 10.3969/j.issn.1674-490X.2014.02.007

Asbtract ( 309 )

PDF (1297KB) ( 410 )

References | Related Articles | Metrics

Objective To explore the effects and inlfuence factors of the patients with hypertensive intracerebral hemorrhage (HICH) after operation and analyze the causes of death after operation. Methods Clinical data of 324 cases with hypertensive intracerebral hemorrhage after operation was analyzed retrospectively, and tried to find out the primary related reasons of death based on the analysis. Results The patient’s consciousness obstructive level when they were admitted into hospital was more severe, the mortality was more higher. The mortality in IV, V level was increased obviously (P<0.01). The mortality was higher in the group that hemorrhage amount was larger. When hemorrhage >80mL, it was significant (P<0.01). The hemorrhage was deeper, the mortality was higher. The mortality increased significantly in the group of thalami and intraventricular hemorrhage (P<0.05). The important factors of the direct cause of death were pernicious intracranial hypertension and pulmonary infection in complications (P<0.01). Conclusion Consciousness obstructive level, regions of hemorrhage, amount of hemorrhage, and complications were important factors that affected the postoperation mortality in patient with hypertensive intracerebral hemorrhage.

Postoperative analgesia effects of parecoxib sodium preemptive analgesia for abdominal surgery in elderly patients

ZHANG Jinli,YAN Hongli,JIN Xiaoshi

2014, 31(2): 30-32,59. DOI: 10.3969/j.issn.1674-490X.2014.02.008

Asbtract ( 342 )

PDF (1327KB) ( 260 )

References | Related Articles | Metrics

Objective To investigate parecoxib sodium preemptive analgesia effects of abdominal surgery in elderly patients with postoperative analgesia. Methods ASA I-II class underwent open surgery. 60 cases of elderly patients were randomly divided into observation group and control group, 30 cases in each group. The observation group started 30 min before anesthesia intravenously parecoxib sodium 40 mg, control group at the same time intravenous Saline. Results The postoperative analgesia magnitude improvement in VAS score and VAS was significantly better than the control group; observation group were nausea, sleepiness, dizziness was significantly lower than the control group; patients using the drug reduced postoperative pain remedy were observed. Conclusion Parecoxib sodium preemptive analgesia for postoperative analgesia in elderly patients with abdominal surgery is better, higher security method in relieving pains in clinical practices.

Clinical observation of aesthetic restoration with unprepared porcelain laminate veneer in front teeth

ZHANG Ling,WANG Qi,ZHANG Wei

2014, 31(2): 33-36. DOI: 10.3969/j.issn.1674-490X.2014.02.009

Asbtract ( 340 )

PDF (1242KB) ( 494 )

References | Related Articles | Metrics

Objective To observe the clinical effects of aesthetic restoration with unprepared porcelain laminate veneer in front teeth. Methods 100 teeth restored with unprepared Porcelain Laminate Veneer were collected and were examined periodically after 2 years, so as to record the completeness of the restored teeth, the satisfaction of the color and the sensitivity of the target teeth after the bond. Results 6 teeth failed out of the 100 teeth restored with unprepared porcelain laminate veneer. Success rate was 94.0%. Conclusion Unprepared porcelain laminate veneer can be used to treat the defect, space, and the discoloration of the front teeth. Successful clinical results can be achieved. Therefore it is a reliable technique for restoring front teeth aesthetically.

Study on the determination of serum homocysteine levels in young patients with post-stroke depression

LIU Xiyan,LI Huimin,SHI Fuping,JIANG Ye,ZHANG Qiuping,GAO Tianchu

2014, 31(2): 37-40. DOI: 10.3969/j.issn.1674-490X.2014.02.010

Asbtract ( 300 )

PDF (1296KB) ( 222 )

References | Related Articles | Metrics

Objective To study the correlation of the serum homocysteine (Hcy) levels and young patients with post-stroke depression. Methods 80 cases of stroke patients (incidence 3 weeks) from 18 to 45 years old were selected who had been diagnosed and were treated from September, 2011 to November, 2013 in the outpatient of our hospital as the subjects of study. Among them, 35 cases with post-stroke depression were in Group A, the left 45 cases with post-stroke depression who had not been occurred in Group B, 35 cases of healthy people served as normal reference group. The serum homocysteine levels between Group A, B and the reference group were compared. According to HAMD score, the severity of depression in Group A were assessed, it was divided into mild depression, moderate depression and severe depression subgroup, then compared the serum homocysteine levels among the three subgroups. Results Compared with normal reference group, Hcy levels of Group A and B were signiifcantly higher, the difference was statistically signiifcant. Hcy levels of the three groups were compared respectively, all of the differences were statistically signiifcant. The Hcy levels of the mild, moderate and severe depression group in Group A were increased with the increase of HAMD score.The degree of depression and homocysteine levels were positively correlated (r=0.7545, P<0.05). Conclusion The occurrence of stroke and post-stroke depression in young adults were related with the Hcy levels of serum, and the higher of the Hcy levels is , the more severe degrees of depression are.

Clinical observations of Carbamazepine combined with pricking and lfash-ifre cupping in the treatment of postherpetic neuralgia

MA Xiaojuan,ZHANG Weina,LI Heshan,QIE Yongtao

2014, 31(2): 41-44. DOI: 10.3969/j.issn.1674-490X.2014.02.011

Asbtract ( 370 )

PDF (1327KB) ( 325 )

References | Related Articles | Metrics

Objective To observe the curative effect and safety of pricking and lfash-ifre cupping therapy to cure the postherpetic neuralgia. Methods The 60 cases were divided into two groups:one was the control group, Carbamazepine 100 mg was taken orally by the patients in control group, three times per day. And the 40 cases from the observation group were additionally treated with pricking and lfash-ifre cupping every two days beside Carbamazepine. Two weeks were served as one course of treatment. After ifnished, the curative effects were evaluated using the method of visual analogue scale (VAS), according to the pain and sleeping quality of patients before and after treatment. Results The cure rate in observation group was 87.5%and that of control group was 60.00%. The difference was signiifcant (P<0.05). The pain and the accumulate point of sleeping of patients from both groups were signiifcantly decreased after cure, and the curative effects of tested group was better than that of controls (P<0.5). Conclusion The pain of patients was greatly alleviated with the treatment of Carbamazepine combined with pricking and lfash-ifre cupping, and the life quality of patients can be improved, furthermore the method is easy to perform, and gets a good compliance, has little side-effects, which is a good alternative to cure the postherpetic neuralgia.

Clinical obserwation on curative effects of Mizolastine combined with the capsule of Runzaozhiyang in the trestment of chronic urticaria

MA Xiaomin,LI Heshan,WEI Yixuan

2014, 31(2): 45-47. DOI: 10.3969/j.issn.1674-490X.2014.02.012

Asbtract ( 342 )

PDF (1292KB) ( 413 )

References | Related Articles | Metrics

Objective To investigate the clinical effect and safety when Mizolastine was combined with the capsule of Runzaozhiyang to cure the chronic urticarial. Methods The 110 cases were divided into two groups, one was the observation group, Mizolastine and the capsule of Runzaozhiyang were taken orally by the patients from the observation group, and the dose was 10mg once a daily and 4 capsules one time, 3 times per day for Mizolastine and the capsule of Runzaozhiyang, respectively. The other group was the check, 54 cases were only fed with the Mizolastine, the usage and dose was same as that of test group. The observation lasted for 4 weeks continuously and the effect was evaluated based on the clinical symptoms, the decrease exponent of physical sign after one week, two weeks, and four weeks. Results The cure rate in observation group was 92.86%, and the control group was 74.07%. The difference was signiifcant (P<0.05). Conclusion The therapy of Mizolastine combined with the capsule of Runzaozhiyang to cure the chronic urticarial can get a better curative effects and this therapy has a little side-effects and good compliance.

Application of establishing standard percutaneous nephrolithotomy channel with balloon dilation in the treatment of renal staghorn calculi

LIU Ping,YANG Wenzeng,AN Feng,GU Deqiang,CUI Zhenyu

2014, 31(2): 48-50. DOI: 10.3969/j.issn.1674-490X.2014.02.013

Asbtract ( 305 )

PDF (1241KB) ( 313 )

Related Articles | Metrics

Objective To know the status of the mental health and the relationship with the hardiness and copying style of medical students. Methods 947 medical students as the subjects were investigated, Symptom Check List 90 (SCL-90), the questionnaire of the structure of the university student’s hardiness and Coping Styles Questionnaire(CSQ) were used. Results Compared with the National Youth norm in 1986, the medical students had higher score in compulsion, but lower score in interpersonal sensitivity, depression, hostility and paranoid ideation, and the differences were signiifcant. Compared with the sample of 23 891 college students in the study on the application of SCL-90 in China by TANG Qiuping et al in 1988, the medical students had lower score in all factors, and the differences is signiifcant. Compulsion, interpersonal sensitivity, depression were the most common psychological problems. Medical students’ SCL-90 total score, the number of positive items and 10 factors were negatively correlated with hardiness personality total score and four dimensions, mature copying style of solving problem and seeking support, while positively correlated with other kinds of coping style. Conclusion Medical students have a better mental health condition compared with other college students, but there are still some of them having problems in different degree. Hardiness and mature copying style are beneifcial with medical students’ mental health. Immature coping style is not favorable for medical students’ mental health.

Investigation on the physical status among college students in a university of Hebei province

LIU Shufang,LIU Weihao,SHI Dongxing,WANG Shuojia,LI Yuxin,SUN Caiqin

2014, 31(2): 64-69. DOI: 10.3969/j.issn.1674-490X.2014.02.017

Asbtract ( 271 )

PDF (1304KB) ( 410 )

References | Related Articles | Metrics

Objective To investigate the current status of physical activity of college students in a university of Hebei province and improve college students’ status of physical activities and put forward corresponding proposals. Methods 424 college students from Heibei University were conducted with retrospective investigation on status of physical activity in the last 1 week randomly. Results In the last one week, the time spent on daily life physical activity, leisure-time physical activity and high physical activity were respectively 5.71, 32.86 and 165minutes per day for male college students and 10, 17.14 and 90 minutes for female ones, there was significant difference between them(P<0.001). The energies spent on daily life physical activity, leisure-time physical activity and high physical activity were respectively 200, 960 and 1 320 METs per week for male students, and 320, 518, 720 METs per week for female college students, signiifcant difference was also found between them(P<0.01). The survey showed that almost 60%students were in high active degree. 77.14%of the male students was in high active degree while female was 53.92%, 19.43% of female students was mainly in sitting situation while male was 6.67%. Conclusion High physical activity of female college students is signiifcantly lower than that of male. It is urgent to explore the key factors for physical activity of college students.

Main effect factors of psychosomatic symptoms of medical students

WANG Feiran,CHEN Xuezheng,ZHOU Zizhe,JIA Siyue,GU Xinzhong,GAO Yanhua

2014, 31(2): 70-75. DOI: 10.3969/j.issn.1674-490X.2014.02.018

Asbtract ( 287 )

PDF (1384KB) ( 408 )

References | Related Articles | Metrics

Objective To know the psychosomatic symptoms and the main effect factors of the mental health of medical students. Methods 947 medical students were investigated, Symptom Check List 90 (SCL-90), Coping Styles Questionnaire(CSQ) and Self-made General Data Questionnaire(SMGDQ) were used. Results 41.65%of them had mild or worse psychosomatic symptoms. 7.40%of them had moderate or worse psychosomatic symptoms. Only 4 students had severe psychosomatic symptoms, making up 0.42%of all students. Compulsion, interpersonal sensitivity, depression were the most common psychosomatic symptoms. Multiple stepwise regression analysis showed that, good relationship with classmates, good health condition, broad interests, father with high education degree, good relationship with mother, good health condition of father and high grade were protective factors of mental health, while drinking history, smoking history, bad class atmosphere were risk factors of mental health. Conclusion Some of the medical students have psychosomatic symptoms in different degree, and interpersonal relationship, health condition, drinking history, smoking history, broad interests or not, class atmosphere are the most inlfuential factors.

Rapid evaluation of college students’ cognition and concerns to PM2.5

YUAN Qianli,MI Guangming,JI Liwei,WANG Quan,ZHANG Long,WU Han

2014, 31(2): 76-79. DOI: 10.3969/j.issn.1674-490X.2014.02.019

Asbtract ( 265 )

PDF (1267KB) ( 441 )

References | Related Articles | Metrics

Objective To evaluate the college students’ cognition and concern level to PM2.5, and to provide scientific basis for the guidance of targeted intervening measures. Methods Investigations to 92 students from medical and nonmedical majors in a comprehensive university in Baoding city were conducted with Lot quality assurance sampling(LQAS) and focus group discussion. Results The rates of respondents’ average awareness to PM2.5 are respectively 61.11%and 56.67%, the rate of medical students was slightly higher than the nonmedical ones. Qualitative analysis indicated that most respondents seldom payed attention on this issue initiatively, they knew little and had many misunderstanding about the source, danger and protection of PM2.5. Conclusion College students’ knowledge of PM2.5 was limited and they generally had low concerns to the issue. Universities should enhance the environmental protection education and the students’ self-care ability should be improved.

Inlfuence of continuously nursing intervention in children with anaphylactoid purpura

XU Haixia,XU Liping,LU Hongli,HAN Ninglin

2014, 31(2): 80-82,86. DOI: 10.3969/j.issn.1674-490X.2014.02.020

Asbtract ( 226 )

PDF (1359KB) ( 364 )

References | Related Articles | Metrics

Objective To observe whether continuously nursing intervention can reduce the recurrence of children with anaphylactoid purpura. Methods To 64 cases of children with anaphylactoid purpura in hospital were randomly divided into two groups by when admitted into hospital successively: experimental group with continuously nursing intervention of traditional and western medicine ,and control group using routine nursing. Food, anti mite measures compliance and recurrence of disease were compared in the two groups of children. Results The self-management ability, compliance with respect to the manner of intervention, and upper respiratory tract infection of experimental group were obviously better than the control group (P<0.01), the experimental group recurrence rate was 25.0%, which was obviously lower than the control group(56.25%) (P<0.01). Conclusion Using the management of the key link of traditional Chinese medicine health care massage and daily life in children with anaphylactoid purpura can effectively enhance children's resistance and avoid allergens, can reduce the recurrence of children with anaphylactoid purpura.

Feasibility study on unprotected delivery

NIE Jin,NIU Baolan,DONG Wenjing,QIAO Peng,LI Yu

2014, 31(2): 83-86. DOI: 10.3969/j.issn.1674-490X.2014.02.021

Asbtract ( 429 )

PDF (1378KB) ( 396 )

References | Related Articles | Metrics

Objective To discuss application and effects of technique of unprotected perineum delivery in pregnant women. Methods 360 primiparas expecting to have vaginal delivery from January to September 2013 in Tangxian People’s Hospital were selected by convenient sampling and randomly and equally divided into the observation group and the control group. In observation group, midwife would direct the pregnant women to hold her breath and breathe when uterine neck whole opened and fetal head crowned and helped them give birth to a baby under state of unprotected perineum. In the control group, traditional delivery method was chosen. Comparison of soft birth canal laceration, postpartum hemorrhage, duration of delivery, neonatal asphyxia and so on between the two groups was made. Results Rate of lateral episiotomy and of postpartum hemorrhage in the observation group were demonstrated 22.2%and 2.2%, which were obviously lower than that of 75.0%and 13.9%in the control group. The difference had statistical signiifcance (P<0.001). Both groups had no III laceration. However, occurrence rate of I laceration observed was higher in the observation group than that in the control group, on the contrary, rate of II laceration was lower (P=0.001). Duration of 3 birth processes or the whole delivery in the observation group were shorter, and difference between the two groups had statistical significance (P<0.001). There was no statistical significance in the difference of neonatal asphyxia between the two groups (P>0.05). Conclusion Unprotected perineum delivery could reduce occurrence rate of lateral episiotomy and infection of perineum incision, improve comfort of delivery and occurrence rate of natural delivery, and meanwhile decrease occurrence rate of postpartum hemorrhage. Therefore, the unprotected perineum delivery was feasible in clinical practices.

Research development of mast cells in anti-infection immune function

WANG Xiaoman,WANG Jingru,WANG Meng,CAO Zhiran

2014, 31(2): 87-92. DOI: 10.3969/j.issn.1674-490X.2014.02.022

Asbtract ( 338 )

PDF (1218KB) ( 864 )

References | Related Articles | Metrics

Mast cells are innate immune cells which widely distribute in the body’s connective tissue. In recent years, its reported that mast cells not only play an important role in allergic reactions but also play an important role in the body against pathogens. Mast cells not only have the function to identify, phagocytose and kill pathogenic microorganisms, but also through release of cytokines participate in the innate immune response, and can present antigen, regulation of adaptive immune response.

Research status on Traditional Chinese medicine dialectical of vascular dementia

LI Yifan,ZHAO Yongchen,LI Dexu,GAO Yueping

2014, 31(2): 93-97. DOI: 10.3969/j.issn.1674-490X.2014.02.023

Asbtract ( 318 )

PDF (1304KB) ( 435 )

References | Related Articles | Metrics

Traditional Chinese medicine dialectical therapy for vascular dementia fully embodies characteristics of holism concept and Deficiency-excess mixing of Chinese Medicine by analyzing recent research on dialectical therapy of vascular dementia which has a signiifcant effect on the treatment of vascular dementia. It also plays a positive role in improving the patients’ cognitive ability and lessening their family and social burden.

Advance on the treatment of transient ischemia attack with traditional Chinese medicine and western medicine

ZHANG Dongli,LI Yifan,ZHANG Zhanying,ZHAO Dehua

2014, 31(2): 98-102. DOI: 10.3969/j.issn.1674-490X.2014.02.024

Asbtract ( 306 )

PDF (1286KB) ( 312 )

References | Related Articles | Metrics

Transient ischemia attack is a subtype of acute cerebrovascular disease, it is accounted as a high risk factor of cerebral infarction. Strengthening the research of transient ischemia attack has signiifcant meaning to improve clinical efifcacy and prognosis to reduce the incidence rates and disability rate of transient ischemia attack. Traditional Chinese and western medicine treatment of transient ischemia attack has became ripe increasingly.

Relying on the orthopaedic standardization training to improve comprehensive skills of interns resident

LI Guohua,LI Shanzhu

2014, 31(2): 103-106. DOI: 10.3969/j.issn.1674-490X.2014.02.025

Asbtract ( 284 )

PDF (1293KB) ( 360 )

References | Related Articles | Metrics

Objective To investigate in the orthopedics internship teaching effects of using the standard resident standardization training to improve the comprehensive ability of orthopaedic interns. Methods 128 students were randomly divided into 2 groups respectively, in the traditional teaching method and the resident standardization standards for practice teaching, to examine the results of the internship to compare teaching effects and teaching satisfaction of the teachers in the two groups of interns internship. Results Using the standard teaching practice of resident standardization training students the results of the internship was given evaluation scores and comprehensive skills were significantly higher than the traditional teaching practice group, the teaching satisfaction of the teacher's were improved obviously, the difference was statistically signiifcant (P<0.05). Conclusion In orthopedic resident standardization training internship teaching effects are remarkable, the application can improve the quality of orthopaedic trainees’ comprehensive skills and practice.

Table of Content