医学研究与教育 ›› 2019, Vol. 36 ›› Issue (3): 39-44.DOI: 10.3969/j.issn.1674-490X.2019.03.007

• 临床医学 • 上一篇    下一篇

非酒精性脂肪肝影像诊断研究进展

戴漪思,殷小平,段朋朋   

  1. 河北大学附属医院CT/MR室, 河北 保定 071000
  • 收稿日期:2019-02-26 出版日期:2019-06-25 发布日期:2019-06-25
  • 通讯作者: 殷小平(1978—),女,河北保定人,主任医师,博士,硕士生导师,主要从事影像诊断(CT/MR方向)研究。E-mail: yinxiaoping78@sina.com
  • 作者简介:戴漪思(1993—),女,江苏无锡人,在读硕士,主要从事影像诊断(CT/MR方向)研究。 E-mail: daiyisi@hotmail.com
  • 基金资助:
    河北省卫生计生委医学科学研究课题计划项目(20180716)

  • Received:2019-02-26 Online:2019-06-25 Published:2019-06-25

摘要: 非酒精性脂肪肝目前是成人及儿童慢性肝病最常见的原因,其发病率正在逐年上升。以非酒精性脂肪肝、非酒精性脂肪肝炎及脂肪性肝硬化的疾病谱强烈危害到人类的生命健康及寿命,且非酒精性脂肪肝已被指出与多种慢性疾病相关。正确意识并诊断该病已成为临床所需要重视的问题,但目前该病的诊断金标准仍为穿刺病理活检,影像学检查因其无创、重复性强等优点而利于患者的诊断及随访观察。就超声、CT及磁共振技术定性定量诊断非酒精性脂肪的研究进展予以阐述。

关键词: 非酒精性脂肪肝, 超声, 弹性成像, 能谱CT, 磁共振成像, 磁共振波谱成像, 定量非对称回波的最小二乘估算法迭代水脂分离序列, 扩散加权成像

Abstract: Non-alcoholic fatty liver disease(NAFLD)is the most common cause of chronic liver disease in adults and children. NAFLD, nonalcoholic steatohepatitis(NASH)and fatty liver cirrhosis have been associated with a variety of chronic diseases. Correct awareness and diagnosis of the disease has become a problem that clinical needs to pay attention to, but the gold standard for the diagnosis of the disease is still biopsy, imaging examination because of its non-invasive, repeatability and other advantages and conducive to the diagnosis of patients and follow-up observation. In this paper, the advances on the qualitative and quantitative diagnosis of nonalcoholic fat by ultrasound, CT and MR are reviewed.

Key words: non-alcoholic fatty liver disease, ultrasound, real-time tissue elastography, dual energy spectral CT, magnetic resonance imaging, magnetic resonance spectroscopy, iterative decomposition of water and fat with echo asymmetry and least squares estimation quantification sequence, diffusion-weighted imaging

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