Association between gene polymorphism of angiotensin-1 receptor and essential hypertension

Abstract

Abstract: Objective To identify the association between gene polymorphism of A1166C angiotensin, type 1 receptor(AT1R)and essential hypertension(EH). Methods AT1R gene polymorphism was determined by polymerase chain reaction(PCR) in 48 normal controls over aged 40 and 39 cases of EH. Results The AC genotype and C allele were not significantly different between the two groups(χ2=0.026, 0.023, P>0.05). Conclusion The AT1R polymorphism might not be associated with EH.

Key words: essential hypertension(EH), genes, polymerase chain reaction(PCR), angiotensin-1 receptor

CLC Number:

R543

References

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