Abstract: Objective To study the clinical application value of Myocardial Enzyme in the cardiac damage of patients with Rheumatoid Arthritis(RA) and provide a reference basis for the prediction of diagnosis and treatment of RA with cardiac damage. Methods The serum of 89 patients of RA between 2010 and 2013 were collected and detected the level of CK and CK-MB in serum with machine. They were divided into two groups, one group was patients of cardiac damage with RA and the other group was no cardiac damage. The healthy group is from the regular health check-up people. Results The incidence of RA with cardiac damage was 37.1%. The level of CK and CK-MB in cardiac damage with RA was signiifcantly higher than the other two groups, There was signiifcant differences in comparison between the group of cardiac damage with RA and the other two groups to the level of CK and CK-MB(P<0.05). There was no signiifcant differences in comparison between the group of no cardiac damage with RA and the healthy group to the level of CK and CK-MB (P<0.05). Conclusion There is important value in predicting cardiac damage to detect the level of Myocardial Enzyme in patients of RA and provide a reference basis for the prediction of diagnosis and treatment of RA with cardiac damage, which deserves further clinical application.

Key words: Myocardial Enzyme, CK, CK-MB, rheumatoid arthritis, cardiac damage