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Journal of Hebei Medical College for Continuing Education    2021, 38 (4): 29-33.   DOI: 10.3969/j.issn.1674-490X.2021.04.005 Abstract （1024）      PDF（pc） （483KB）（108）       Knowledge map    Save Objective To explore the therapeutic effect of Kangfuxin solution external application in the treatment of facial hormone-dependent dermatitis. Methods A total of 96 patients with hormone-dependent dermatitis were collected in the outpatient department. Of those, 48 patients were given a local cold compress with Kangfuxin solution and the others were given a cold compress with normal saline. The treatment effects of the two groups were compared. Results Through the comparison and analysis of the scores of the two groups, the difference in scores at different times was statistically significant(F=16.340, P<0.001), and the difference between the two groups was statistically significant(F=12.785, P<0.001).The score of Kangfuxinye group was significantly higher than that of normal saline group. Of the 48 patients in the Kangfuxinye group, 39 were cured, 8 cases were markedly effective, and 1 case improved; in the normal saline group, 36 cases were cured, 10 cases were markedly effective, and 2 cases improved. There was no statistically significant difference in efficacy between the two groups(Z=0.765, P>0.05). The recurrence rates observed in the Kangfuxinye group were 4.17%, 6.25%, and 10.42% at 1 month, 3 months, and 6 months after treatment; and the recurrence rates of the normal saline group were: 18.75%, 25.00%, and 35.42%. The difference in recurrence rate was statistically significant(P<0.05)between these two groups.Conclusion Kangfuxin solution has a good effect in the treatment of hormone-dependent dermatitis and can reduce the recurrence of the disease. Reference | Related Articles | Metrics | Comments（0）

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Challenges and countermeasures of population aging to public health service CHENG Huaizhi, GUO Bin, SONG Jiawei, LI Yu Journal of Hebei Medical College for Continuing Education    2022, 39 (1): 49-53.   DOI: 10.3969/j.issn.1674-490X.2022.01.007 Abstract （1021）      PDF（pc） （430KB）（297）       Knowledge map    Save China is facing a huge medical challenge from its aging problem. By 2050, China's population aged 65 and above will reach 400 million, of which the population aged 80 and above will reach 150 million. This paper reviews the evolution and current situation of population aging systematically through literature review, and analyzes some public health problems caused by China's aging population from the perspective of economic: underutilization of health service, the rapid rise of health costs, the huge demand for nursing service. It is suggested that we should strengthen health education for the elderly, expand nursing service, provide individual nursing care for them, further improve the medical security system and build a sustainable long-term care insurance system. Reference | Related Articles | Metrics | Comments（0）

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Journal of Hebei Medical College for Continuing Education    2021, 38 (5): 15-19.   DOI: 10.3969/j.issn.1674-490X.2021.05.003 Abstract （891）      PDF（pc） （431KB）（89）       Knowledge map    Save Objective To observe the clinical efficacy and safety of recombinant human interferon α1b nasopharyngeal spray in treatment of viral upper respiratory tract infection. Methods 112 children with viral upper respiratory tract infection diagnosed in pediatric outpatient department of our hospital from April 2018 to December 2020 were collected. According to the random method, they were divided into experimental group and control group, with 56 cases in each group. The experimental group was given 100 U recombinant interferon α1b+2 mL normal saline to spray nasopharynx, with 3 times/d and continuous treatment for 3-5 days. And both groups were given routine treatment such as cough relieving, phlegm resolving, fever reducing and anti-infection. After 3-5 days of treatment, the improvement of symptoms of upper respiratory tract infection, signs(nasal congestion, runny nose, cough, fever, pharyngeal congestion)and adverse reactions were compared between the two groups. Results The duration of fever(t=5.707, P=0.000), remission time of systemic symptoms(t=6.994,P=0.000)total course(t=4.593, P=0.000)of the experimental group were shorter than those of the control group, and the difference was statistically significant. The curative effects of the experimental group were better than the control group(Z=-2.869, P=0.004). The scores of nasal congestion, runny nose(t=14.707, P=0.000), cough(t=13.710, P=0.000)and pharyngeal congestion(t=13.430, P=0.000)in the experimental group were better than those in the control group. Only one child in the experimental group had nausea, and the others had no adverse reactions. Conclusion The application of recombinant human interferon α1b nasopharyngeal spray is effective and safe in the treatment of children with acute upper respiratory tract infection. Reference | Related Articles | Metrics | Comments（0）

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Advances on determination methods of flavonoids in Chinese herbal medicine YANG Hui,YANG Tianrun,MA Ziyun Journal of Hebei Medical College for Continuing Education    2022, 39 (3): 9-13.   DOI: 10.3969/j.issn.1674-490X.2022.03.002 Abstract （683）      PDF（pc） （436KB）（501）       Knowledge map    Save Flavonoids are a kind of natural organic compounds widely existing in plants and are abundant in many Chinese herbal medicines. As an effective component of many traditional Chinese medicines, flavonoids play an important role in the treatment of diseases due to their extensive physiological or pharmacological activities, and are widely used in clinical practice. Therefore, the determination of such compounds in Chinese herbal medicine is one of the important links in drug quality control. In this paper, different determination methods of flavonoids in Chinese herbal medicine are reviewed. Reference | Related Articles | Metrics | Comments（0）

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Current situation and development strategy of community hospice care in China JIN Yan, QIAO Yanhua Journal of Hebei Medical College for Continuing Education    2022, 39 (1): 54-60.   DOI: 10.3969/j.issn.1674-490X.2022.01.008 Abstract （666）      PDF（pc） （489KB）（496）       Knowledge map    Save By combing the development model and experience of community hospice care in China, this paper analyzes the main problems existing in the development of community hospice care, and puts forward reasonable suggestions for the development of community hospice care in China, such as increasing support and guarantee, strengthening the construction of talent team, establishing a correct concept of life and death so as to promote the faster and better development of domestic community hospice care services. Reference | Related Articles | Metrics | Comments（0）

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Journal of Hebei Medical College for Continuing Education    2021, 38 (3): 62-69.   DOI: 10.3969/j.issn.1674-490X.2021.03.011 Abstract （621）      PDF（pc） （963KB）（291）       Knowledge map    Save Objective To analyze the research hotspot, frontier and future development trends in the field of nursing psychology in the past six years, and provide reference suggestions for the development and application of related research in the field of nursing psychology.Methods Through the CNKI database, using “psychology” as the search term, retrieve the papers published in ten core nursing journals from 2015 to 2020, and use the CiteSpace visualization software to perform metrological analysis of authors, institutions, and keywords.Results A total of 2 341 papers on nursing psychology published in ten core nursing journals from 2015 to 2020 were included.The number of papers published in the past 6 years has shown a slight fluctuation trend.The publishing organizations are relatively concentrated, mostly from major universities, and there is little cooperation between authors.Key words such as qualitative research,quality of life, influencing factors, and have been the research hotspots of nursing psychology in the past six years, and ICU Nurses,psychological distress,psychological perplexity and mediation effect are the research frontiers.Conclusion Visualized analysis of nursing psychology papers published in core nursing journals in the past six years can help us to understand the research hotspot and frontier trends of nursing psychology related research, and promote the further development of nursing psychology research in teaching, clinical, and management levels. Reference | Related Articles | Metrics | Comments（0）

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Journal of Hebei Medical College for Continuing Education    2021, 38 (4): 8-17.   DOI: 10.3969/j.issn.1674-490X.2021.04.002 Abstract （602）      PDF（pc） （771KB）（383）       Knowledge map    Save Coronary artery bifurcation lesions are common in coronary intervention. Due to the greatly individual differentiation of coronary artery bifurcation lesions, complex surgical procedures, high intraoperative risk, many postoperative complications, and poor long-term prognosis, a standard process is hard to follow to solve all bifurcation lesions. The classification rules, evaluation methods, and treatment strategies of coronary bifurcation lesions are systematically reviewed in order to get more comprehensively understanding of coronary bifurcation lesions. Reference | Related Articles | Metrics | Comments（0）

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Journal of Hebei Medical College for Continuing Education    2021, 38 (4): 73-80.   DOI: 10.3969/j.issn.1674-490X.2021.04.011 Abstract （591）      PDF（pc） （483KB）（379）       Knowledge map    Save This article reviews the current status of HPV vaccination, the theoretical framework and intervention methods of HPV vaccination intervention. It is recommended that future studies build a multi-level social support system(including government level, medical staff level and parent level, etc.)based on internet technology, and enrich publicity methods(narrative dissemination)to improve the health awareness and health behaviors of the age-appropriate population for HPV vaccination and prevent HPV infection. Reference | Related Articles | Metrics | Comments（0）

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Journal of Hebei Medical College for Continuing Education    2021, 38 (3): 12-17.   DOI: 10.3969/j.issn.1674-490X.2021.03.003 Abstract （562）      PDF（pc） （659KB）（107）       Knowledge map    Save Objective To analyze the effect of correcting mouth breathing and the variation of facial hard and soft tissue of class II malocclusion with mouth breathing by Twin-block in the growth peak.Methods 30 cases in growth peak with class II malocclusion and mouth breathing were selected.They were treated with Twin-block appliance, the treatment lasted for 12 months.The correction rate of mouth breathing was counted at 3, 6, 9 and 12 months after treatment respectively,the re-examination was conducted 6 months after treatment.Lateral cranial radiographs or models were measured before treatment, after treatment and 6 months after treatment.The results were analyzed with SPSS 26.0.Results The effective correction rate of mouth breathing increased with time, SNB, NP-FH, L1-MP increased, ANB, Y axis, U1-SN decreased, B'Li-FH, LiB'Pg', NsPg'-FH, GSnPg' increased, NsLs-FH, NsLi-FH decreased, these differences were statistically significant(P<0.05).After treatment for 6 months, the anterior overbite overjet remained stable.Conclusion The mouth breathing were corrected effectively, the growth of the mandible was stimulated, and the soft tissue profile was improved in growth peak by Twin-block appliance. Reference | Related Articles | Metrics | Comments（0）

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HAO's clinical experience of traditional Chinese medicine in Baoding in ophthalmology MENG Hongwei Journal of Hebei Medical College for Continuing Education    2022, 39 (4): 45-54.   DOI: 10.3969/j.issn.1674-490X.2022.04.007 Abstract （560）      PDF（pc） （515KB）（341）       Knowledge map    Save HAO's ophthalmology of traditional Chinese Medicine(TCM)is the specialty of TCM in Baoding. HAO Dexin is a renowned Chinese ophthalmologist at the Hebei Institute of Traditional Chinese Medicine in Baoding in ancestral ophthalmology.HAO is a representative of traditional Chinese medicine ophthalmology.He has rich experience in diagnosis and treatment of diseases such as fulminant blindness, myopia and fundus oculi diseases.The curative effect is remarkable.HAO is good at treating eye diseases with traditional Chinese medicine and acupuncture.He has unique experience in the application of Chinese medicine prescription and the manipulation of acupoints.The diagnosis and treatment of ophthalmologic diseases should be based on the three Jing of Xin,Gan and Shen. Reference | Related Articles | Metrics | Comments（0）

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Journal of Hebei Medical College for Continuing Education    2021, 38 (3): 41-49.   DOI: 10.3969/j.issn.1674-490X.2021.03.008 Abstract （477）      PDF（pc） （516KB）（157）       Knowledge map    Save This paper discusses the origin and application method of the theory of the blood-Qi and the blood-Qi in the six Meridians combined with clinical practice.The theory of the number of blood-Qi in the six Meridians is a multi-level method of syndrome differentiation combining the differentiation of six Meridians and blood-Qi.The six Meridians Syndrome differentiation is beneficial to the accurate location of the disease from the anatomical point of view,and the blood-Qi Syndrome differentiation is beneficial to the accurate determination of the disease from the physiological point of view.The dynamic physiological changes and the characteristics of the six Meridians and the Qi can be reflected through the differentiation of blood-Qi.Yang produces the motion,Yin produces the matter.Through the local shape,quality and movement into the concept of blood-Qi,by the blood-Qi number,not only can the blood-Qi characteristics of the six Meridians be highlighted,but also the local microscopic blood-Qi changes can be inferred from this.Thus diseases can be analyzed from the pathological changes of blood-Qi,forming syndrome differentiation of the blood-Qi,reflect the microscopic level of physiological and pathological changes,as an important method of syndrome differentiation.The combination of six Meridians Syndrome differentiation and blood-Qi Syndrome differentiation can qualitatively locate the disease from multi-level and multi-angle,and can improve the rationality and accuracy of disease diagnosis and treatment. Reference | Related Articles | Metrics | Comments（0）

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Journal of Hebei Medical College for Continuing Education    2021, 38 (3): 29-33.   DOI: 10.3969/j.issn.1674-490X.2021.03.006 Abstract （467）      PDF（pc） （438KB）（95）       Knowledge map    Save Objective To investigate the difference in the efficacy of atomized inhalation of nitroglycerin and sildenafil in the treatment of neonatal pulmonary hypertension.Methods All of 54 cases of PPHN were randomly divided into nitroglycerin group(n=27)and sildenafil group(n=27), and all children received general treatments such as oxygen inhalation, acidosis correction, electrolyte balance maintenance and so on.On the basis of the above treatment,the patients of nitroglycerin group were treated with atomized inhalation of nitroglycerin, and those of sildenafil group were given nasal feeding or oral sildenafil.The efficacy and safety after treatment were compared and analyzed.Results Before treatment, there were no significant differences in the heart rate(HR), respiratory rate(RR), systolic pulmonary artery pressure(SPAP)and arterial oxygen partial pressure(PaO2)between two groups(P>0.05).After treatment, HR, RR and SPAP in the nitroglycerin group and the sildenafil group decreased significantly, while the index value of PaO2 increased significantly.Compared with before treatment, HR, RR, SPAP and PaO2 in the two groups showed statistically significant differences(P<0.05), indicating that the treatment was effective.There was no significant difference in the clinical cure rate between the two groups(P>0.05).Conclusion Atomized nitroglycerin inhalation, nasal feeding or oral sildenafil are both effective in the treatment of neonatal mild to moderate pulmonary hypertension, with strong practicability, good safety, cheap and there was no difference in efficacy, which are ideal schemes for the treatment of this disease. Reference | Related Articles | Metrics | Comments（0）

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Journal of Hebei Medical College for Continuing Education    2023, 40 (2): 58-65.   DOI: 10.3969/j.issn.1674-490X.2023.02.009 Abstract （456）      PDF（pc） （478KB）（204）       Knowledge map    Save As a chronic lifelong disease, the long-term disease management of diabetes predisposes patients to increase physical and psychological burdens, resulting in negative psychological distress, which affects patients' disease progression and quality of life. This article reviews the current status of psychological distress in diabetes, psychological distress assessment tools and influencing factors, and presents its own reflections to provide a reference for identifying, preventing and implementing targeted interventions for psychological distress in diabetes, and to point out the way for future related research. Reference | Related Articles | Metrics | Comments（0）

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Journal of Hebei Medical College for Continuing Education    2021, 38 (5): 36-44.   DOI: 10.3969/j.issn.1674-490X.2021.05.006 Abstract （450）      PDF（pc） （466KB）（189）       Knowledge map    Save The malnutrition in patients with cancer has a high incidence, which is closely related to the poor treatment results and prognosis.So nutritional supplementation is significant extremely.Oral nutritional supplements are the first choice for nutritional supplements for cancer patients with basically normal gastrointestinal function.For cancer patients during treatment, oral nutritional supplements can help them maintain weight, improve body composition, improve nutritional status, reduce postoperative infection risks, enhance the tolerance of anti-cancer treatment reduce short-term readmission rates, and improve short-term survival.Moreover, the earlier the nutritional intervention, the more beneficial to the treatment and prognosis of patients.However, the effects of oral nutritional supplements in shortening the length of hospitalization, improving the quality of life and reducing mortality are controversia, and further in-depth research is still needed. This study mainly reviewed the effects of oral nutritional supplements used by cancer patients, and provided a basis for increasing the importance of oral nutritional supplements by hospitals, patients and their families. Reference | Related Articles | Metrics | Comments（0）

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Journal of Hebei Medical College for Continuing Education    2021, 38 (5): 20-25.   DOI: 10.3969/j.issn.1674-490X.2021.05.004 Abstract （445）      PDF（pc） （452KB）（123）       Knowledge map    Save Objective To investigate the effect of tirofiban on oxidative stress and neurological function in patients with acute cerebral infarction undergoing mechanical thrombectomy.Methods 88 patients with acute cerebral infarction from September 2019 to September 2020 were selected as the research objects.All patients were divided into control group and observation group according to different treatment methods, with 44 cases in each group.Mechanical embolectomy was performed in both groups, and tirofiban was applied in the observation group at the same time.The levels of CRP, MDA, SOD, GSH PX and neurological function of the two groups before operation, 36 hours after operation and before discharge were compared NIHSS, UCH-L1, GFAP, BDNF and recanalization rate were measured.Results Compared with before operation, the indexes of the observation group were significantly better than those of the control group at 36h after operation and before discharge(P<0.05), compared with 36h after operation, the levels of oxidative stress factors and neurological function indexes of the two groups before discharge were significantly improved, and the indexes of the observation group were significantlybetter than those of the control group(P<0.05), the postoperative recanalization rate of the observation group(95.45%)was significantly higher than that of the control group(72.73%).Conclusion Tirofiban can effectively improve the high oxidative stress state and reduce the neurological deficit in patients with acute cerebral infarction. Reference | Related Articles | Metrics | Comments（0）

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Journal of Hebei Medical College for Continuing Education    2021, 38 (5): 7-14.   DOI: 10.3969/j.issn.1674-490X.2021.05.002 Abstract （442）      PDF（pc） （528KB）（98）       Knowledge map    Save Objective To explore the application value of 3.0 T intensity magnetic resonance diffusion weighted imaging and dynamic enhanced scanning in breast cancer.Methods A total of 188 patients with 210 breast tumors(136 malignant and 74 benign)were selected from Baoding Second Hospital from December 2016 to December 2019 by using Siemens 3.0 T magnetic resonance.According to breast imaging reporting and data system(BI-RADS)grading and diffusion weighted imaging(DWI)description indexes, both mass(n=182)and non-mass(n=28)were labeled on dynamic Contrast-enhanced(DCE)scans and T2-weighted imaging.Meanwhile, the characteristics of DCE, T2-weighted imaging and apparent diffusion coefficient(ADC)in BI-RADS description indicators were used to distinguish benign and malignant lesions, and the ADC cut-off value ≤1.255×10-3 mm2/s was used as the standard.The results were compared with the pathological results of surgery or puncture biopsy and analyzed statistically.Results In model 1, ADCmean(P<0.003), DCE mass margin(P=0.002), and DCE plateau or outflow enhancement(P=0.001)were significantly and independently associated with the diagnosis of breast cancer.Model 2 determined that ADCmean(P=0.001), DCE mass margin(P=0.001), early rapid enhancement(P=0.042), and DCE plateau or outflow enhancement(P=0.001)were significantly independently associated with breast cancer diagnosis.T2-weighted imaging variables were not included in the final model.Conclusion Using 3.0 T magnetic resonance and multichannel breast coil examination, the quantitative and qualitative descriptive index models in DCE and DWI can achieve accurate diagnosis of breast cancer, and the combined application can significantly improve the diagnostic accuracy of breast cancer.T2-weighted imaging does not significantly contribute to the diagnosis of breast cancer. Reference | Related Articles | Metrics | Comments（0）

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Journal of Hebei Medical College for Continuing Education    2021, 38 (3): 34-40.   DOI: 10.3969/j.issn.1674-490X.2021.03.007 Abstract （436）      PDF（pc） （710KB）（151）       Knowledge map    Save In order to deeply explore the academic thoughts,professional achievements,formation context and academic contribution of Yanzhao family of Traditional Chinese medicine,Professor GE Shaoqin,dean of school of Traditional Chinese Medicine of Hebei University,conducted academic exchanges and in-depth interviews with MENG Xiangjun,the inheritor of traditional Chinese medicine,on the inheritance context of Meng's traditional Chinese medicine,nine needle medicine and integrity innovation,and scientific nature of nine needle medicine,and put forward the idea of cooperation between folk doctors and universities the nine needle medical thought of research. Related Articles | Metrics | Comments（0）

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Journal of Hebei Medical College for Continuing Education    2021, 38 (4): 61-66.   DOI: 10.3969/j.issn.1674-490X.2021.04.009 Abstract （434）      PDF（pc） （441KB）（282）       Knowledge map    Save This study introduced the concept of “Internet plus” and hospice care, analyzed the advantages of application of “Internet plus” in the field of hospice care, and synthesized the use of “Internet plus” in symptoms management, psychological and social support, education and information provision for hospice patients, and information support and work coordination for health professionals, and summarized the problems and development prospects, with the purpose of providing reference for the development and application of “Internet + hospice care” service delivery model in China. Reference | Related Articles | Metrics | Comments（0）

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Journal of Hebei Medical College for Continuing Education    2021, 38 (6): 59-68.   DOI: 10.3969/j.issn.1674-490X.2021.06.009 Abstract （429）      PDF（pc） （810KB）（143）       Knowledge map    Save Objective To investigate the status quo of stigma in stroke patients and explore the influencing factors of stigma in stroke patients, and clarify the mechanism of the influencing factors. Methods A total of 324 inpatients with stroke were selected by fixed point continuous sampling according to the standard of inpatient arrangement. Stroke patients' stigma scale, health cognitive evaluation scale, simplified version of mental resilience scale, perceived social support scale and medical coping style questionnaire were used to investigate. Results The total score of stigma in stroke patients was 45.36±11.76.Stigmatism in stroke patients was positively correlated with negative cognitive evaluation, submission coping style and avoidance coping style. And psychological resilience, social support and coping style were significantly negatively correlated. Among the influencing factors of stigma in stroke patients, the total effect value of negative cognitive evaluation was 0.023;Total effect value of mental resilience -0.601;Total effect value of social support was -0.234;The total effect of avoidance coping style was 0.110.Conclusion The stroke patients' stigma is above the average level, among which the score of self-perception dimension is the highest. The situation of stigma is not optimistic, and medical workers should pay attention to it. The negative cognitive evaluation of stroke events in stroke patients indirectly affected stigma through avoidance coping style; Resilience can affect stigma directly and indirectly through negative cognitive evaluation and avoidance coping style. The direct effect is greater than the indirect effect. Social support not only directly affected stigma, but also indirectly affected stigma through negative cognitive evaluation and avoidance coping style. The direct effect is greater than the indirect effect. Avoidance coping style has a direct positive effect on stigma. Reference | Related Articles | Metrics | Comments（0）

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Journal of Hebei Medical College for Continuing Education    2021, 38 (3): 1-6.   DOI: 10.3969/j.issn.1674-490X.2021.03.001 Abstract （412）      PDF（pc） （439KB）（286）       Knowledge map    Save Umbilical cord blood has gradually become an important source of stem cells in allogeneic stem cell transplantation.Although the post-transplantation infective fatality rate is higher, the survival rate of cord blood transplantation is comparable to other types of stem cell transplantation due to the advantages of easy access and lower incidence of GVHD(graft-versus-host diseases, GVHD).The improvement of cord blood transplantation technology has also brought better curative effect to the patients. The clinical application of umbilical cord blood provides a new method for the treatment of many refractory diseases.This article reviews the improvement of cord blood transplantation in recent years, the selection of cord blood for transplantation and the application of umbilical cord blood in other related diseases. Reference | Related Articles | Metrics | Comments（0）

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Journal of Hebei Medical College for Continuing Education    2021, 38 (6): 27-35.   DOI: 10.3969/j.issn.1674-490X.2021.06.005 Abstract （410）      PDF（pc） （490KB）（253）       Knowledge map    Save Lung cancer is the most common cancer and the leading cause of cancer death worldwide. Early diagnosis of lung cancer can reduce mortality. Radiomics can extract the quantitative features of the images by computer software to explore more disease information of lung cancer and improve the early diagnosis rate. This article reviews the application of imaging omics in the early diagnosis of lung cancer in order to improve the understanding of the application of radiomics in the diagnosis of lung cancer. Reference | Related Articles | Metrics | Comments（0）

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Journal of Hebei Medical College for Continuing Education    2021, 38 (3): 70-80.   DOI: 10.3969/j.issn.1674-490X.2021.03.012 Abstract （405）      PDF（pc） （1519KB）（274）       Knowledge map    Save Objective To analyze the international research status of self-compassion in recent 11 years, so as to understand the research basis, hot spots and frontier of self-compassion related literature, help nursing and educators to enhance their understanding of self-compassion, and provide basis for further improving nursing and teaching concepts.Methods Using the core collection of web of science database as the platform, CiteSpace software was used to analyze the self compassion literatures collected from January 2010 to June 2020.Results A total of 1 677 articles were searched, and the number of published articles increased year by year.The research level of nursing and education should be improved, Classic literature on self compassion focuses on self compassion theory, intervention methods and scale research.The research focuses are self-compassion theory research, intervention measures and scale use.The future research frontier is randomized controlled trials of self-compassion measurement and interventionmethods in different types of people.Conclusion Self-compassion as a positive psychological quality, and its measurement and intervention are important ways to improve the level of individual mental health.In the future nursing and teaching work, we should pay attention to measuring the level of self-compassion of different groups, and formulate intervention strategies to improve the level of self-compassion as the core in nursing work and daily teaching, so as to enhance the quality of nursing and teaching. Reference | Related Articles | Metrics | Comments（0）

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Role of binocular vision function in the progression of myopia GAO Chunting, YUAN Hui, DU Junhui Journal of Hebei Medical College for Continuing Education    2022, 39 (3): 14-20.   DOI: 10.3969/j.issn.1674-490X.2022.03.003 Abstract （392）      PDF（pc） （476KB）（348）       Knowledge map    Save Myopia is a common disease in the population, and its incidence is increasing year by year, especially in children and adolescents, seriously affecting their physical and mental health. Binocular vision refers to that two eyes see at the same time, while external objects fall on the retina, forming retinal images, nerve excitatory transmission go to the brain higher center, so that the visual signals of two eyes merge into a single perceptual object. When viewing stereoscopic objects, due to the difference of normal pupil distance and the angle of faxation, the images formed on the retina of the two eyes are not completely symmetrical and have certain horizontal difference. This phenomenon is called Binocular Parallax, which gives us stereoscopic perception. Many studies have shown that binocular vision functions such as accommodation, convergence, stereoscopic vision and the development of myopia interact.The purpose of this article is to review the developments of binocular vision function and myopia in order to provide reference for the prevention and control of myopia to choose effective and appropriate programs. Reference | Related Articles | Metrics | Comments（0）

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Journal of Hebei Medical College for Continuing Education    2021, 38 (6): 36-43.   DOI: 10.3969/j.issn.1674-490X.2021.06.006 Abstract （363）      PDF（pc） （515KB）（387）       Knowledge map    Save Osteoporosis is a skeletal disease which is susceptible to middle-aged and elderly people. It is characterized by decreased bone density, destruction of bone microstructure, increased bone fragility, and prone to fractures.Drug therapy is an important means to effectively prevent osteoporosis and reduces fractures, but there are problems such as long treatment period and adverse drug reactions. However, physical therapy has the advantages of outstanding curative effect and low side effects. This review mainly describes the application of physical therapy in the treatment of osteoporosis, aiming to provide a basis for clinically formulating high-quality rehabilitation strategies for prevention and treatment of osteoporosis. Reference | Related Articles | Metrics | Comments（0）

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Journal of Hebei Medical College for Continuing Education    2021, 38 (6): 22-26.   DOI: 10.3969/j.issn.1674-490X.2021.06.004 Abstract （362）      PDF（pc） （426KB）（172）       Knowledge map    Save Objective To explore and compare the clinical efficacy of conventional chemotherapy combined with moxifloxacin or levofloxacin in the treatment of patients with multi-drug resistant pulmonary tuberculosis. Methods 98 patients with MDR-TB were selected from November 2019 to February 2021. According to the random digital table method, the patients in observation group were divided into two groups, 49 patients in observation group were treated with conventional chemotherapy and moxifloxacin, 49 cases in control group were treated with conventional chemotherapy and levofloxacin, and then compared after treatment. The clinical efficacy, immune function, focus absorption rate, sputum bacteria negative rate, cavity closure rate and adverse reactions were observed in the two groups. Results After treatment, the total effective rate of the observation group was 71.43%, which was significantly higher than that of the control group(P<0.05). After 18 months of treatment, the sputum negative conversion rate, lesion absorption rate and cavity closure rate of the observation group were 42.86%, 40.82% and 46.94%, respectively, which were significantly higher than those of the control group(P<0.05). After 18 months of treatment, the CD4+ in the observation group was(41.83±9.02)%, IgA was(4.08±0.62)g/L, IgG was(19.84±3.40)g/L,which were significantly higher than the control group. CD8+ was(29.83±5.62)%, which was significantly lower than that of the control group(P<0.05). There was no significant difference in the incidence of adverse reactions between the two groups during the treatment(P>0.05). Conclusion The treatment of multi-drug resistant tuberculosis patients with conventional chemotherapy combined with moxifloxacin can significantly improve the immune function of patients, control the occurrence of adverse reactions, and the effects are accurate, which are worth popularizing and adopting in clinical practices. Reference | Related Articles | Metrics | Comments（0）

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Journal of Hebei Medical College for Continuing Education    2021, 38 (4): 67-72.   DOI: 10.3969/j.issn.1674-490X.2021.04.010 Abstract （361）      PDF（pc） （414KB）（246）       Knowledge map    Save 6S model is a practical concept in hospice care, the essence is person-centered palliative and it's aim is to promote patients' death with dignity. It has been verified that it could be applied to many aspects of nursing work to help patients and nurses. This model can provide some reference and guidance for promoting the domestic hospice care in the exploratory stage. Reference | Related Articles | Metrics | Comments（0）

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The key role of Nrf2 in ischemic stroke ZHU Jianping, LI Yunman Journal of Hebei Medical College for Continuing Education    2022, 39 (2): 1-9.   DOI: 10.3969/j.issn.1674-490X.2022.02.001 Abstract （347）      PDF（pc） （693KB）（246）       Knowledge map    Save Ischemic stroke is one of the main causes of death and disability worldwide. Nuclear factor E2-related factor 2(Nrf2)is an important transcription factor that regulates the balance of the body's redox reaction. It participates in resisting endogenous or exogenous stress by coordinating a variety of cytoprotective genes. The Nrf2 signaling pathway not only strictly regulates the body's redox homeostasis, but also participates in the regulation of multiple processes in the body metabolism. Therefore, targeting Nrf2 has become a potential strategy for the prevention and treatment of central nervous system diseases including ischemic stroke. In this review, we first introduced the structural features of Nrf2 and Kelch-like ECH-related protein 1(Keap1), and briefly described the activation and regulation of the Nrf2 pathway. Next, we discussed the pathological and physiological mechanism, upstream regulators and downstream targets of the Nrf2 pathway. In this context, we extended the discussion to the role of Nrf2 after ischemic stroke and explored potential therapeutic directions. Reference | Related Articles | Metrics | Comments（0）

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Research status of fear disease progression in stroke patients HUANG Xianyi, LIU Shuang, LIU Yan, YUE Jie, CHEN Li Journal of Hebei Medical College for Continuing Education    2022, 39 (5): 68-74.   DOI: 10.3969/j.issn.1674-490X.2022.05.011 Abstract （327）      PDF（pc） （453KB）（139）       Knowledge map    Save Stroke patients are prone to fear of disease or disease progression when faced with complex treatment periods, long recovery periods and unpredictable changes in the condition. Fear of disease progression will damage the physical and mental health, and social function of stroke patients, and eventually reduce the patient's rehabilitation and prognosis. This article reviews the concept, measurement tools, research status at home and abroad and influencing factors of fear disease progression, so as to provide reference for clinical nurses to deeply understand the present situation of fear disease progression of stroke patients and carry out relevant nursing practice and clinical management. Reference | Related Articles | Metrics | Comments（0）

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Journal of Hebei Medical College for Continuing Education    2021, 38 (4): 34-46.   DOI: 10.3969/j.issn.1674-490X.2021.04.006 Abstract （316）      PDF（pc） （683KB）（153）       Knowledge map    Save The research of Yishui School focuses on innovation, which requires creative thinking and methods. The thinking should be flexible, and the method can be explored from the scientific connotation of the school, the academic thought of the main doctors of the school, the recognition of the medical circles and the common prescriptions and traditional Chinese medicine of the main doctors. In this paper, some prescriptions and drugs of Yishui School are cited for clinical application. Related Articles | Metrics | Comments（0）

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Developments on radiogenomics based on MRI in lung cancer brain metastases SUI Lianyu, YIN Xiaoping, WANG Jianing Journal of Hebei Medical College for Continuing Education    2022, 39 (1): 25-34.   DOI: 10.3969/j.issn.1674-490X.2022.01.004 Abstract （312）      PDF（pc） （528KB）（190）       Knowledge map    Save Brain metastases are intracranial malignant tumors with high incidence and poor prognosis, brain metastases from lung cancer are the most common in clinical practice. MR is the preferred imaging diagnosis method for intracranial tumors, and MRI imagingomics is gradually applied to the precise and individualized diagnosis and treatment of brain metastases. With the continuous in-depth research on the connection between genes and tumors, tumor diagnosis is extended to the direction of molecular genetics. Radiogenomics is a method of fusing imaging phenotypes with genes and molecules, using non-invasive and accurate methods to detect tumors. The molecular genetic changes of the disease have been widely used in tumor discovery, treatment guidance and prognosis prediction, etc. This article reviews the feasibility and research progress of MRI radiogenomics radio genomics in brain metastases. Reference | Related Articles | Metrics | Comments（0）

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Journal of Hebei Medical College for Continuing Education    2021, 38 (6): 8-14.   DOI: 10.3969/j.issn.1674-490X.2021.06.002 Abstract （312）      PDF（pc） （457KB）（232）       Knowledge map    Save Intestinal flora is currently a hot issue studied by scholars around the world. The structure and composition of intestinal flora will change after ischemic stroke, which may threaten the life and health of people after stroke. Intestinal flora affects the progression of the disease by increasing the production of pro-inflammatory cytokines and intestinal permeability. Through the flora and stroke-related inflammatory response, the changes in the intestinal flora of patients after ischemic stroke, the impact of the flora on the complications of stroke, and the possibility of the current intestinal flora for clinical treatment, the progress of the intestinal flora and ischemic stroke were reviewed. In the process of clinical diagnosis and treatment, the influence of intestinal flora should be considered so as not to affect the diagnosis and treatment of the disease. Reference | Related Articles | Metrics | Comments（0）

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Journal of Hebei Medical College for Continuing Education    2021, 38 (4): 1-7.   DOI: 10.3969/j.issn.1674-490X.2021.04.001 Abstract （311）      PDF（pc） （1424KB）（165）       Knowledge map    Save Objective To establish a mouse model of RA with hGPI325-339 and hGPI469-483 mixed peptides and observe the frequency and mature status of cDC in RA mice.Methods The frequency of cDC and the expression of CD80 and CD86 in spleen and lymph nodes of RA model mice were detected by flow cytometry.Results The frequency of cDC in spleen of RA mice was significantly lower than that of normal control group during the four stages of inflammation.The expression of CD80 was significantly higher than normal control group in the initial stage, peak stage and remission stage of inflammation, and was significantly lower than normal control group in the progressive stage of inflammation.The expression of CD86 was significantly higher than normal control group in all four stages of inflammation.The frequency of cDC in lymph nodes was significantly higher than normal control group in all four stages of inflammation.The expression of CD80 was significantly higher than normal control group at the initial stage of inflammation and lower than normal control group at other three stages.The expression of CD86 was significantly lower than normal control group in the initial, progressive and remission stages of inflammation, and higher than normal control group in the peak of inflammation.Conclusion The antigen presenting role of splenic cDC may be more important than that of lymph nodes in RA.The cDC maturity of spleen and lymph node in RA show a fluctuating phenomenon that increases at first and then decreases. Reference | Related Articles | Metrics | Comments（0）

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Journal of Hebei Medical College for Continuing Education    2022, 39 (6): 24-28.   DOI: 10.3969/j.issn.1674-490X.2022.06.004 Abstract （307）      PDF（pc） （458KB）（27）       Knowledge map    Save Objective To compare the therapeutic effect of oral compound thrombolysis capsules combined with retinal photocoagulation, intravitreal injection ranibizumab and oral compound thrombolysis capsules combined with retinal photocoagulation in the treatment of retinal branch vein occlusion and macular edema. Methods A retrospective analysis was conducted in 42 patients with 42 eyes diagnosed with retinal branch vein occlusion and macular edema, and the patients were divided into two groups according to different treatment regimens: the experimental group(21 eyes)was treated with intravitreal injection ranibizumab combined with compound oral thrombolysis capsules and retinal photocoagulation, the control group(21 eyes)was given the compound thrombolysis capsule combined with retinal laser photocoagulation, the experimental group received ranibizumab intravitreal injection, while oral thrombolysis capsule, and retinal laser photocoagulation was performed 3 months later. The two groups underwent simple retinal photocoagulation and oral thrombosis capsules. The optimal corrected visual acuity of the two groups was examined during the 6-month treatment period, the changes of macular foveal retinal thickness were determined.Results After 6 months of treatment, the optimal corrected visual acuity of both groups was improved, and the treating effects of the experimental group was better than that of the control group, and the ophthalmic optical coherence tomography showed that the macular foveal thickness was reduced by 415.51 μm(61.45%)in the combination treatment group and 120.51 μm(27.40%)in the control group, which indicated that the treating effects of the experimental group was better than that of the controls. Conclusion Intravitreal injection of ranibizumab combined with oral compound thrombolysis capsule and retinal photocoagulation is safe and effective in the treatment of retinal branch vein occlusion and macular edema. Reference | Related Articles | Metrics | Comments（0）

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Development on digital orthopedic technology in clinical work YANG Xuping, LI Xingyong Journal of Hebei Medical College for Continuing Education    2022, 39 (4): 22-29.   DOI: 10.3969/j.issn.1674-490X.2022.04.004 Abstract （303）      PDF（pc） （516KB）（133）       Knowledge map    Save Digital medicine is an emerging discipline that combines scientific informatics with medical technology, including 3D printing, finite element analysis and computer-aided orthopedic technology, and its application in the field of orthopedics is very extensive. Based on the many advantages of digital orthopedic technology in clinical work, it helps to solve the difficulties encountered in clinical work and has considerable application prospects, and its effective application in the clinic can benefit the majority of patients. Reference | Related Articles | Metrics | Comments（0）

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Journal of Hebei Medical College for Continuing Education    2021, 38 (6): 74-80.   DOI: 10.3969/j.issn.1674-490X.2021.06.011 Abstract （303）      PDF（pc） （635KB）（221）       Knowledge map    Save Objective To explore the application of the network-based Problem-based learning(PBL)combined with Multiple Disciplinary Team(MDT)mode in teaching medical undergraduate students during the Covid-19 epidemic to provide new suggestions for the teaching mode of medical undergraduates. Methods 117 clinical medicine undergraduates of grade 2018 in China Medical University were selected as the research objects and divided randomly into control group(61)and experimental group(56). The control group was taught by network PBL teaching,and the experimental group was taught by network-based PBL combined with MDT teaching Mode. At the end of the teaching, the case-studied summary and the satisfaction of the teaching mode of the two groups were analyzed. Results The questionnaire survey found that PBL+MDT teaching group's case-studied summary and the improvement of self-ability was significantly higher than that of the control group, the difference was statistically significant(P<0.05). Students' satisfaction of PBL+MDT teaching was higher, the difference was statistically significant(P<0.05). Conclusion Network-based PBL combined with MDT mode can improve the enthusiasm of medical undergraduates, cultivate students' evidence-based thinking and innovation ability, and have a positive effect on the training of medical undergraduates. Reference | Related Articles | Metrics | Comments（0）

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Journal of Hebei Medical College for Continuing Education    2021, 38 (3): 7-11.   DOI: 10.3969/j.issn.1674-490X.2021.03.002 Abstract （302）      PDF（pc） （404KB）（105）       Knowledge map    Save Objective To explore risk factors for cerebral microbleeds(CMB)in patients without hypertension and diabetes.Methods Patients hospitalized in the Department of Neurology,Baoding NO.1 Central Hospital from April 2019 to March 2020 without hypertension and diabetes were retrospectively recruited.Each patient underwent MRI check including susceptibility-weighted imaging(SWI).They were divided into two groups according to the existence of CMBs named CMB group(with CMBs, n=35)and NCMB group(without CMBs, n=114)respectively.Clinical and neuroimaging information was collected.Statistical analysis was conducted thereafter.Results It was demonstrated by univariate analysis that age, systolic blood pressure and systolic-to-diastolic pressure were associated with CMBs(P<0.05).Multivariate Logistic regression analysis showed that the older of the patient,the results of the experimental subjects would become(OR=1.535,95%CI=1.089-2.165,P=0.014)and the higher systolic blood pressure(OR=1.715, 95%CI=1.077-2.506, P=0.019), the higher risk of CMB.Conclusion Age and systolic blood pressure were independent risk factors for CMBs in patients without hypertension and diabetes. Reference | Related Articles | Metrics | Comments（0）

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Journal of Hebei Medical College for Continuing Education    2023, 40 (1): 76-80.   DOI: 10.3969/j.issn.1674-490X.2023.01.012 Abstract （300）      PDF（pc） （393KB）（85）       Knowledge map    Save The class of western medicine learning traditional Chinese medicine in Hebei Provincial School for Advanced Study of Traditional Chinese Medicineis was the earliest provincial-level educational institution of western medicine learning traditional Chinese medicine in Hebei province. In 1958, it was incorporated into Hebei College of Traditional Chinese Medicine and became the first batch students majoring in western medicine learning Chinese medicine Class(department)in Hebei College of Traditional Chinese Medicine. Through study of western medicine combined with learning traditional Chinese medicine education a large number of excellent talents for traditional Chinese medicine has been trained, which is one of the important forms of traditional Chinese medicine education. The class of western medicine learning traditional Chinese medicine in Hebei Provincial School for Advanced Study of Traditional Chinese Medicine was an active exploration of the standardized education of traditional Chinese medicine in western medicine learning traditional Chinese medicine, which has successfully trained some well-known persons, e.g. LIU Wenming, LI Huamin, SHU Jingzong etc. Collecting historical materials and the information of the class of western medicine learning traditional Chinese medicine in Hebei Provincial School for Advanced Study of Traditional Chinese Medicine, studying its teaching mode, can provide some successful experience for the development of traditional Chinese medicine education. Reference | Related Articles | Metrics | Comments（0）

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Journal of Hebei Medical College for Continuing Education    2021, 38 (5): 1-6.   DOI: 10.3969/j.issn.1674-490X.2021.05.001 Abstract （297）      PDF（pc） （469KB）（132）       Knowledge map    Save Elderly people are the main group of hip fractures. Hip arthroplasty is the main method to treat hip fractures in the elderly. The promotion of enhanced recovery after surgery(ERAS)has been putting forward new requirements for the anesthesia of hip arthroplasty.This review briefly introduces the application of ERAS in the perioperative period of hip replacement surgery; mainly discusses the basis for the selection of anesthesia methods under the ERAS concept and the value evaluation system of the application of new technologies. General anesthesia, intraspinal anesthesia, peripheral nerve block and their combined application were compared and the direction of development and optimization of different anesthesia methods under the ERAS concept is proposed. Reference | Related Articles | Metrics | Comments（0）

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Journal of Hebei Medical College for Continuing Education    2021, 38 (3): 50-55.   DOI: 10.3969/j.issn.1674-490X.2021.03.009 Abstract （295）      PDF（pc） （458KB）（136）       Knowledge map    Save To analyze the necessity of general hospital participating in hospice care service system and the functional orientation of general hospital and community health service center in regional hospice care service system,this paper reviews the exploration and practice of “1 + 11” hospice care service system in Putuo District from the perspective of tiered medical services.The effectiveness and necessity of the establishment of the service system are demonstrated through the preliminary effectiveness analysis, providing reference for the exploratory work of hospice care in other pilot areas. Reference | Related Articles | Metrics | Comments（0）

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Current status of research on clinical progress management of benign prostatic hyperplasia JIANG Dongxu, ZOU Hao, SUN Min, ZHANG Linlin Journal of Hebei Medical College for Continuing Education    2022, 39 (1): 68-74.   DOI: 10.3969/j.issn.1674-490X.2022.01.010 Abstract （294）      PDF（pc） （469KB）（272）       Knowledge map    Save In recent years,with the acceleration of aging,the prevalence of benign prostatic hyperplasia(BPH)has shown an increasing trend,seriously affecting the quality of life of elderly men,and at the same time,it has brought an economic burden to the global medical care service system. In order to explore the current status of BPH management methods at home and abroad,an integrated analysis was carried out by searching relevant literature on BPH clinical progress management. At present,in order to delay and change the clinical progress of BPH patients,management methods combining clinical and non-clinical interventions have been adopted at home and abroad,and some results have been achieved,but there are still certain limitations. This paper analyzes and summarizes the current research status, and provides a reliable basis for the management of BPH clinical progress in the later stage. Reference | Related Articles | Metrics | Comments（0）